Basic information
Locus name	AT1G12200
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	flavin-containing monooxygenase family protein / FMO family protein; FUNCTIONS IN: NADP or NADPH binding, monooxygenase activity, FAD binding, flavin-containing monooxygenase activity. Gene expression is increased during leaf senescence.
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function N,N-dimethylaniline monooxygenase activity NADP binding flavin adenine dinucleotide binding
Sequence	AT1G12200.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_126653	Accession Taxon NP_001077522 Arabidopsis thaliana NP_172677 Arabidopsis thaliana NP_172678 Arabidopsis thaliana NP_172680 Arabidopsis thaliana NP_172684 ( AT1G12200 ) Arabidopsis thaliana NP_176444 Arabidopsis thaliana NP_176446 Arabidopsis thaliana NP_176448 Arabidopsis thaliana NP_176450 Arabidopsis thaliana NP_176523 Arabidopsis thaliana NP_176526 Arabidopsis thaliana NP_176761 Arabidopsis thaliana NP_196397 Arabidopsis thaliana NP_200937 Arabidopsis thaliana NP_564796 Arabidopsis thaliana NP_564797 Arabidopsis thaliana CMG139C Cyanidioschyzon merolae strain 10D 145075 Chlamydomonas reinhardtii 149795 Chlamydomonas reinhardtii 206139 Chlamydomonas reinhardtii 206143 Chlamydomonas reinhardtii 206144 Chlamydomonas reinhardtii ACO64033 Micromonas sp. RCC299 ACO70320 Micromonas sp. RCC299 NP_001043045 Oryza sativa Japonica Group NP_001047237 Oryza sativa Japonica Group NP_001052272 Oryza sativa Japonica Group NP_001052273 Oryza sativa Japonica Group NP_001057774 Oryza sativa Japonica Group NP_001058739 Oryza sativa Japonica Group NP_001058740 Oryza sativa Japonica Group NP_001058741 Oryza sativa Japonica Group NP_001058742 Oryza sativa Japonica Group NP_001063856 Oryza sativa Japonica Group NP_001065338 Oryza sativa Japonica Group 1200010184 Ostreococcus tauri fgenesh1_pg.C_Chr_18.0001000086 Ostreococcus tauri estExt_Genewise1.C_110166 Physcomitrella patens subsp. patens 28455.m000364 Ricinus communis 28455.m000366 Ricinus communis 28455.m000367 Ricinus communis 29720.m000138 Ricinus communis 30138.m004025 Ricinus communis 30170.m014354 Ricinus communis 30178.m000873 Ricinus communis 30178.m000874 Ricinus communis 30178.m000875 Ricinus communis 30178.m000876 Ricinus communis fgenesh1_pg.C_chr_16a000077 Thalassiosira pseudonana CCMP1335 XP_002953620 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23023 4.4E-162 7 438 No hit NA SUPERFAMILY SSF51905 3.8E-53 8 243 No hit NA Pfam PF00743 1.4E-38 12 244 IPR020946 Flavin monooxygenase-like PRINTS PR00370 2.0E-20 12 28 IPR000960 Flavin monooxygenase FMO PRINTS PR00370 2.0E-20 36 60 IPR000960 Flavin monooxygenase FMO PRINTS PR00370 2.0E-20 224 239 IPR000960 Flavin monooxygenase FMO Pfam PF00743 3.7E-17 268 377 IPR020946 Flavin monooxygenase-like SUPERFAMILY SSF51905 1.0E-19 269 441 No hit NA PRINTS PR00370 2.0E-20 275 302 IPR000960 Flavin monooxygenase FMO PRINTS PR00370 2.0E-20 340 353 IPR000960 Flavin monooxygenase FMO