Basic information
Locus name	AT1G72520
Alias	LOX4
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:JA
Effect for Senescence	promote
Gene Description	Expression is greatly increased in leaves during leaf senescence
Evidence	Molecular evidence:Northern [Ref 1]
References	1: He Y, Fukushige H, Hildebrand DF, Gan S Evidence supporting a role of jasmonic acid in Arabidopsis leaf senescence. Plant Physiol. 2002 Mar;128(3):876-84
Gene Ontology	biological process oxidation-reduction process molecular function metal ion binding oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
Pathway	KEGG map00591 (EC 1.13.11.12) map00592 (EC 1.13.11.12) MetaCyc PWY-5410
Sequence	AT1G72520.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT1G72520.1  miRNA: ath-miR869 miRNA: ath-miR869 mfe: -25.1 kcal/mol  p-value: 0.063340  position:  1449  target 5' G      A           U  A 3'             GUCAGC AUCUUGAC CC GA              CAGUUG UAGAGUUG GG CU   miRNA  3'        A        U  U    5'
Ortholog Group
Ortholog Groups: OG5_127482	Accession Taxon NP_175900 Arabidopsis thaliana NP_176923 Arabidopsis thaliana NP_177396 ( AT1G72520 ) Arabidopsis thaliana NP_188879 Arabidopsis thaliana NP_564021 Arabidopsis thaliana NP_566875 Arabidopsis thaliana 144677 Chlamydomonas reinhardtii NP_001046180 Oryza sativa Japonica Group NP_001049158 Oryza sativa Japonica Group NP_001050990 Oryza sativa Japonica Group NP_001050993 Oryza sativa Japonica Group NP_001050995 Oryza sativa Japonica Group NP_001051212 Oryza sativa Japonica Group NP_001052913 Oryza sativa Japonica Group NP_001055143 Oryza sativa Japonica Group NP_001062199 Oryza sativa Japonica Group NP_001062200 Oryza sativa Japonica Group NP_001067011 Oryza sativa Japonica Group NP_001067015 Oryza sativa Japonica Group NP_001068135 Oryza sativa Japonica Group e_gw1.171.1.1 Physcomitrella patens subsp. patens e_gw1.21.1.1 Physcomitrella patens subsp. patens e_gw1.434.22.1 Physcomitrella patens subsp. patens e_gw1.97.30.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_4190013 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_4190004 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2320058 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_4190009 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_4190017 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_700115 Physcomitrella patens subsp. patens 29468.m000030 Ricinus communis 29680.m001710 Ricinus communis 29726.m003891 Ricinus communis 29808.m000898 Ricinus communis 29851.m002422 Ricinus communis 29851.m002424 Ricinus communis 29929.m004699 Ricinus communis 30128.m008781 Ricinus communis 30152.m002449 Ricinus communis 30169.m006387 Ricinus communis 30169.m006389 Ricinus communis 30178.m000859 Ricinus communis XP_002952279 Volvox carteri f. nagariensis XP_002952280 Volvox carteri f. nagariensis XP_002956550 Volvox carteri f. nagariensis XP_002956551 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description SMART SM00308 7.0E-50 90 229 IPR001024 Lipoxygenase, LH2 SUPERFAMILY SSF49723 1.6E-47 90 232 IPR008976 Lipase/lipooxygenase, PLAT/LH2 PANTHER PTHR11771 0.0 104 926 IPR000907 Lipoxygenase ProSiteProfiles PS50095 18.4 106 228 IPR001024 Lipoxygenase, LH2 Pfam PF01477 1.3E-14 141 227 IPR001024 Lipoxygenase, LH2 PRINTS PR00468 8.5E-64 198 216 IPR001246 Lipoxygenase, plant PRINTS PR00468 8.5E-64 224 245 IPR001246 Lipoxygenase, plant ProSiteProfiles PS51393 279.3 231 926 IPR013819 Lipoxygenase, C-terminal SUPERFAMILY SSF48484 1.8E-259 233 926 IPR013819 Lipoxygenase, C-terminal Pfam PF00305 7.8E-255 239 910 IPR013819 Lipoxygenase, C-terminal PRINTS PR00468 8.5E-64 263 279 IPR001246 Lipoxygenase, plant PRINTS PR00468 8.5E-64 295 314 IPR001246 Lipoxygenase, plant PRINTS PR00468 8.5E-64 361 382 IPR001246 Lipoxygenase, plant PRINTS PR00468 8.5E-64 409 425 IPR001246 Lipoxygenase, plant PRINTS PR00468 8.5E-64 448 467 IPR001246 Lipoxygenase, plant PRINTS PR00468 8.5E-64 516 540 IPR001246 Lipoxygenase, plant PRINTS PR00087 1.0E-19 562 579 IPR013819 Lipoxygenase, C-terminal PRINTS PR00087 1.0E-19 580 597 IPR013819 Lipoxygenase, C-terminal ProSitePatterns PS00711 NA 580 594 IPR020833 Lipoxygenase, iron binding site PRINTS PR00087 1.0E-19 600 620 IPR013819 Lipoxygenase, C-terminal ProSitePatterns PS00081 NA 607 617 IPR020834 Lipoxygenase, conserved site PRINTS PR00468 8.5E-64 838 852 IPR001246 Lipoxygenase, plant
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787