Basic information
Locus name	AT2G38050
Alias	DET2/DWF6
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:BR
Effect for Senescence	promote
Gene Description	Involved in the brassinolide biosynthetic pathway.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Li J, Chory J A putative leucine-rich repeat receptor kinase involved in brassinosteroid signal transduction. Cell 1997 Sep 5;90(5):929-38
Gene Ontology	biological process lipid metabolic process oxidation-reduction process steroid metabolic process cellular component cytoplasm molecular function 3-oxo-5-alpha-steroid 4-dehydrogenase activity oxidoreductase activity, acting on the CH-CH group of donors
Pathway	KEGG map00140 (EC 1.3.99.5) Reactome REACT_15314 REACT_22258
Sequence	AT2G38050.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	det2
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	EMS
Ortholog Group
Ortholog Groups: OG5_128852	Accession Taxon NP_181340 ( AT2G38050 ) Arabidopsis thaliana CMO284C Cyanidioschyzon merolae strain 10D 117574 Chlamydomonas reinhardtii 120014 Chlamydomonas reinhardtii ACO66602 Micromonas sp. RCC299 NP_001044822 Oryza sativa Japonica Group 0300010055 Ostreococcus tauri estExt_fgenesh1_pg.C_1170051 Physcomitrella patens subsp. patens 27798.m000584 Ricinus communis thaps1_ua_kg.chr_17000029 Thalassiosira pseudonana CCMP1335 XP_002945613 Volvox carteri f. nagariensis XP_002953502 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF015596 3.3E-149 1 262 IPR016636 3-oxo-5-alpha-steroid 4-dehydrogenase PANTHER PTHR10556 3.2E-101 25 262 No hit NA Pfam PF02544 7.0E-62 112 262 IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal ProSiteProfiles PS50244 33.2 156 236 IPR001104 3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal
Subcellular Localization
Localization	endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787