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Locus name | AT1G73500 |
Alias | MKK9 |
Organism | Arabidopsis thaliana |
Taxonomic identifier | [NCBI] |
Function category | Signal transduction:MKK cascade |
Effect for Senescence | promote |
Gene Description | member of MAP Kinase Kinase family. Autophosphorylates and also phosphorylates MPK3 and MPK6 |
Evidence | Genetic evidence:Mutant [Ref 1]; Genomic evidence:microarray data [Ref 2] |
References | 1: Zhou C, Cai Z, Guo Y, Gan SAn arabidopsis mitogen-activated protein kinase cascade, MKK9-MPK6, plays a role in leaf senescence.Plant Physiol. 2009 May;150(1):167-772: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJComparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis.Plant J. 2005 May;42(4):567-85 |
Gene Ontology | |
Sequence | AT1G73500.1 | Genomic | mRNA | CDS | Protein
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Mutated 1 | Mutant name |
mkk9-1 | Mutant/Transgenic |
mutant | Ecotype |
Col-0 |
Mutagenesis type |
T-DNA insertion_knock out |
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Mutated 2 | Mutant name |
35S:MKK9 | Mutant/Transgenic |
transgenic | Ecotype |
Col-0 |
Mutagenesis type |
transgene |
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Mutated 3 | Mutant name |
35S:MKK9mpk6 | Mutant/Transgenic |
mutant and trangenic(Double mutant) | Ecotype |
Col-0 |
Mutagenesis type |
cross |
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Mutated 4 | Mutant name |
DEXin:MKK9 | Mutant/Transgenic |
transgenic | Ecotype |
Col-0 |
Mutagenesis type |
transgene |
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Sampling |
Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4) |
Comparation |
Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence. |
miRNA Interaction | |
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Details | | target: AT1G73500.1 miRNA: ath-miR854a miRNA: ath-miR854a mfe: -29.1 kcal/mol p-value: 0.010936
position: 161 target 5' U G 3' CUUCUUCUCUCUAUUC CAU GAGGAGGAGGGAUAGG GUA miRNA 3' A G 5'
target: AT1G73500.1 miRNA: ath-miR854b miRNA: ath-miR854b mfe: -29.1 kcal/mol p-value: 0.012367
position: 161 target 5' U G 3' CUUCUUCUCUCUAUUC CAU GAGGAGGAGGGAUAGG GUA miRNA 3' A G 5'
target: AT1G73500.1 miRNA: ath-miR854c miRNA: ath-miR854c mfe: -29.1 kcal/mol p-value: 0.010873
position: 161 target 5' U G 3' CUUCUUCUCUCUAUUC CAU GAGGAGGAGGGAUAGG GUA miRNA 3' A G 5'
target: AT1G73500.1 miRNA: ath-miR854d miRNA: ath-miR854d mfe: -29.1 kcal/mol p-value: 0.011557
position: 161 target 5' U G 3' CUUCUUCUCUCUAUUC CAU GAGGAGGAGGGAUAGG GUA miRNA 3' A G 5'
target: AT1G73500.1 miRNA: ath-miR854e miRNA: ath-miR854e mfe: -29.1 kcal/mol p-value: 0.012756
position: 161 target 5' U G 3' CUUCUUCUCUCUAUUC CAU GAGGAGGAGGGAUAGG GUA miRNA 3' A G 5'
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Ortholog Group | |
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Ortholog Groups: OG5_150257 | |
Cross Link | |
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Mutant Image | |
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Overexpression of MKK9 (A) induced H2O2 production (D), cell death (C)and early senescence (B). | |
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