Basic information
Locus name	AT5G17690
Alias	TFL2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction:light signal
Effect for Senescence	promote
Gene Description	TERMINAL FLOWER 2. Regulates the meristem response to light signals and the maintenance of inflorescence meristem identity.
Evidence	Genetic evidence:Mutant [Ref 1, Ref 2, Ref 3]
References	1: Kotake T, Takada S, Nakahigashi K, Ohto M, Goto K Arabidopsis TERMINAL FLOWER 2 gene encodes a heterochromatin protein 1 homolog and represses both FLOWERING LOCUS T to regulate flowering time and several floral homeotic genes. Plant Cell Physiol. 2003 Jun;44(6):555-64 2: Larsson AS, Landberg K, Meeks-Wagner DR The TERMINAL FLOWER2 (TFL2) gene controls the reproductive transition and meristem identity in Arabidopsis thaliana. Genetics 1998 Jun;149(2):597-605 3: Takada S, Goto K Terminal flower2, an Arabidopsis homolog of heterochromatin protein1, counteracts the activation of flowering locus T by constans in the vascular tissues of leaves to regulate flowering time. Plant Cell 2003 Dec;15(12):2856-65
Gene Ontology	cellular component nucleus
Sequence	AT5G17690.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	tfl2
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	T-DNA insertion_knock out
miRNA Interaction
Details	target: AT5G17690.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -32.3 kcal/mol  p-value: 0.000228  position:  379  target 5' G     A              U 3'             GAUGA GAUGAUGGAGGUGA              CUGCU CUACUACUUCUACU   miRNA  3' A     A                5'
Ortholog Group
Ortholog Groups: OG5_129545	Accession Taxon NP_197271 ( AT5G17690 ) Arabidopsis thaliana NP_001064351 Oryza sativa Japonica Group 30148.m001410 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22812 5.6E-63 68 256 No hit NA SUPERFAMILY SSF54160 3.9E-18 95 157 IPR016197 Chromo domain-like PRINTS PR00504 4.7E-5 105 113 IPR017984 Chromo domain subgroup SMART SM00298 3.7E-14 107 160 IPR000953 Chromo domain/shadow Pfam PF00385 1.0E-14 108 156 IPR023780 Chromo domain ProSiteProfiles PS50013 16.2 108 156 IPR000953 Chromo domain/shadow PRINTS PR00504 4.7E-5 118 132 IPR017984 Chromo domain subgroup ProSitePatterns PS00598 NA 125 145 IPR023779 Chromo domain, conserved site PRINTS PR00504 4.7E-5 133 145 IPR017984 Chromo domain subgroup SMART SM00300 5.5E-10 372 444 IPR008251 Chromo shadow domain
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787