Basic information
Locus name	AT5G66880
Alias	SNRK2.3
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	promote
Gene Description	ncodes a member of SNF1-related protein kinases (SnRK2) whose activity is activated by ionic (salt) and non-ionic (mannitol) osmotic stress. Enzyme involved in the ABA signaling during seed germination, dormancy and seedling growth.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Gao S, Gao J, Zhu X, Song Y, Li Z, Ren G, Zhou X, Kuai B. ABF2, ABF3, and ABF4 Promote ABA-Mediated Chlorophyll Degradation and Leaf Senescence by Transcriptional Activation of Chlorophyll Catabolic Genes and Senescence-Associated Genes in Arabidopsis. Mol Plant. 2016 Sep 6;9(9):1272-1285. doi: 10.1016/j.molp.2016.06.006. Epub 2016 Jun 30.
Gene Ontology	biological process protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity
Sequence	AT5G66880.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name snrk2.2/2.3/2.6 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
Mutated 2 Mutant name snrk2.2/3/6 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type cross
Mutated 3 Mutant name snrk2.2/2.3/2.6 Mutant/Transgenic Ecotype Col-0 Mutagenesis type cross
Ortholog Group
Ortholog Groups: OG5_137540	Accession Taxon NP_190619 Arabidopsis thaliana NP_201489 ( AT5G66880 ) Arabidopsis thaliana NP_567945 Arabidopsis thaliana 113331 Chlamydomonas reinhardtii ACO62993 Micromonas sp. RCC299 NP_001050653 Oryza sativa Japonica Group NP_001051371 Oryza sativa Japonica Group NP_001067155 Oryza sativa Japonica Group gw1.03.00.311.1 Ostreococcus tauri estExt_Genewise1.C_1130026 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_1160010 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2180038 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2400063 Physcomitrella patens subsp. patens 29676.m001638 Ricinus communis 29780.m001320 Ricinus communis XP_002949856 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24343 4.9E-205 12 361 No hit NA SUPERFAMILY SSF56112 3.6E-84 14 313 IPR011009 Protein kinase-like domain Pfam PF00069 8.8E-71 22 278 IPR000719 Protein kinase, catalytic domain ProSiteProfiles PS50011 47.7 22 278 IPR000719 Protein kinase, catalytic domain SMART SM00220 1.0E-99 22 278 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain ProSitePatterns PS00107 NA 28 51 IPR017441 Protein kinase, ATP binding site ProSitePatterns PS00108 NA 137 149 IPR008271 Serine/threonine-protein kinase, active site
Mutant Image
The snrk2.2/3/6 triple mutant showed reduced ABA-induced leaf senescence relative to the WT
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787