Basic information
Locus name	AT2G44050
Alias	COS1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:JA
Effect for Senescence	promote
Gene Description	6,7-dimethyl-8-ribityllumazine synthase / DMRL synthase / lumazine synthase / riboflavin synthase [Arabidopsis thaliana]. Acts in the jasmonic acid signaling pathway.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Xiao S, Dai L, Liu F, Wang Z, Peng W, Xie D COS1: an Arabidopsis coronatine insensitive1 suppressor essential for regulation of jasmonate-mediated plant defense and senescence. Plant Cell 2004 May;16(5):1132-42
Gene Ontology	biological process riboflavin biosynthetic process cellular component riboflavin synthase complex
Pathway	KEGG map00740 (EC 2.5.1.9) MetaCyc PWY-6167
Sequence	AT2G44050.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	cos1
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	EMS
Ortholog Group
Ortholog Groups: OG5_128902	Accession Taxon NP_181933 ( AT2G44050 ) Arabidopsis thaliana CMI238C Cyanidioschyzon merolae strain 10D 186616 Chlamydomonas reinhardtii ACO66685 Micromonas sp. RCC299 NP_001053206 Oryza sativa Japonica Group fgenesh1_pg.C_Chr_14.0001000164 Ostreococcus tauri estExt_Genewise1.C_150284 Physcomitrella patens subsp. patens estExt_Genewise1.C_540203 Physcomitrella patens subsp. patens 28623.m000404 Ricinus communis gw1.2.721.1 Thalassiosira pseudonana CCMP1335 XP_002946387 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF038166 7.1E-189 1 227 IPR017420 6,7-dimethyl-8-ribityllumazine synthase, chloroplast PANTHER PTHR21058 9.1E-65 67 223 IPR002180 6,7-dimethyl-8-ribityllumazine synthase SUPERFAMILY SSF52121 8.8E-54 76 223 IPR002180 6,7-dimethyl-8-ribityllumazine synthase Hamap MF_00178 27.2 81 225 IPR002180 6,7-dimethyl-8-ribityllumazine synthase Pfam PF00885 2.6E-51 83 223 IPR002180 6,7-dimethyl-8-ribityllumazine synthase TIGRFAM TIGR00114 7.3E-46 85 221 IPR002180 6,7-dimethyl-8-ribityllumazine synthase
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787