Basic information
Locus name	AT5G35750
Alias	AHK2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway:CK
Effect for Senescence	delay
Gene Description	Encodes histidine kinase AHK2.
Evidence	Genetic evidence:Mutant [Ref 1]
References	1: Riefler M, Novak O, Strnad M, Schmulling T Arabidopsis cytokinin receptor mutants reveal functions in shoot growth, leaf senescence, seed size, germination, root development, and cytokinin metabolism. Plant Cell 2006 Jan;18(1):40-54
Gene Ontology	biological process phosphorelay signal transduction system phosphorylation regulation of transcription, DNA-dependent molecular function phosphorelay response regulator activity transferase activity, transferring phosphorus-containing groups
Pathway	Reactome REACT_14797 REACT_1046
Sequence	AT5G35750.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name ahk2-2 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 2 Mutant name ahk2-5 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 3 Mutant name ahk2-5ahk3-7 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 4 Mutant name ahk2ahk3cre1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 5 Mutant name ahk2cre1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Ortholog Group
Ortholog Groups: OG5_129304	Accession Taxon NP_564276 Arabidopsis thaliana NP_565277 Arabidopsis thaliana NP_568532 ( AT5G35750 ) Arabidopsis thaliana NP_849925 Arabidopsis thaliana NP_973396 Arabidopsis thaliana 114537 Chlamydomonas reinhardtii 97170 Chlamydomonas reinhardtii NP_001045241 Oryza sativa Japonica Group NP_001048061 Oryza sativa Japonica Group NP_001064436 Oryza sativa Japonica Group gw1.09.00.217.1 Ostreococcus tauri e_gw1.194.71.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_1440014 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2710020 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_500074 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_252000025 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_44000141 Physcomitrella patens subsp. patens 29597.m000294 Ricinus communis 29929.m004637 Ricinus communis 29968.m000653 Ricinus communis XP_002954901 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description ProSiteProfiles PS50839 41.4 302 526 IPR006189 CHASE SMART SM01079 2.1E-36 302 501 IPR006189 CHASE Pfam PF03924 3.7E-44 304 501 IPR006189 CHASE Coils Coil NA 564 585 No hit NA PANTHER PTHR24423 1.3E-120 572 1174 No hit NA SUPERFAMILY SSF47384 8.8E-19 574 653 IPR009082 Signal transduction histidine kinase, homodimeric domain Pfam PF00512 8.0E-19 587 652 IPR003661 Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain SMART SM00388 1.7E-22 587 652 IPR003661 Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain ProSiteProfiles PS50109 43.8 594 862 IPR005467 Signal transduction histidine kinase, core SUPERFAMILY SSF55874 2.5E-41 641 734 IPR003594 Histidine kinase-like ATPase, ATP-binding domain Pfam PF02518 3.2E-31 699 862 IPR003594 Histidine kinase-like ATPase, ATP-binding domain SMART SM00387 2.4E-34 699 867 IPR003594 Histidine kinase-like ATPase, ATP-binding domain SUPERFAMILY SSF55874 2.5E-41 791 862 IPR003594 Histidine kinase-like ATPase, ATP-binding domain PRINTS PR00344 1.1E-14 792 806 IPR004358 Signal transduction histidine kinase-related protein, C-terminal PRINTS PR00344 1.1E-14 810 820 IPR004358 Signal transduction histidine kinase-related protein, C-terminal PRINTS PR00344 1.1E-14 827 845 IPR004358 Signal transduction histidine kinase-related protein, C-terminal PRINTS PR00344 1.1E-14 851 864 IPR004358 Signal transduction histidine kinase-related protein, C-terminal SUPERFAMILY SSF52172 4.3E-8 886 1012 IPR011006 CheY-like superfamily SUPERFAMILY SSF52172 4.7E-32 1033 1173 IPR011006 CheY-like superfamily SMART SM00448 6.6E-32 1035 1169 IPR001789 Signal transduction response regulator, receiver domain ProSiteProfiles PS50110 27.9 1036 1173 IPR001789 Signal transduction response regulator, receiver domain Pfam PF00072 1.1E-19 1037 1169 IPR001789 Signal transduction response regulator, receiver domain
Subcellular Localization
Localization	endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787