Basic information
Locus name	AT1G14130
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	2-oxoglutarate-dependent dioxygenase, putative; FUNCTIONS IN: oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors, oxidoreductase activity
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors oxidoreductase activity
Sequence	AT1G14130.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G14130.1  miRNA: ath-miR827 miRNA: ath-miR827 mfe: -27.7 kcal/mol  p-value: 0.000852  position: 1254  target 5' U             A U     A  3'             GUUUGUUGGUGGU C UCUAG                 CAAACAACUACCA G AGAUU      miRNA  3' U               U        5'
Ortholog Group
Ortholog Groups: OG5_177502	Accession Taxon NP_172864 Arabidopsis thaliana NP_172865 ( AT1G14130 ) Arabidopsis thaliana NP_001053075 Oryza sativa Japonica Group 29682.m000588 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10209 1.7E-81 9 307 No hit NA Pfam PF14226 2.2E-13 9 69 IPR026992 Non-haem dioxygenase N-terminal domain SUPERFAMILY SSF51197 9.6E-66 9 300 No hit NA ProSiteProfiles PS51471 9.9 151 255 IPR005123 Oxoglutarate/iron-dependent dioxygenase Pfam PF03171 1.2E-16 153 252 IPR005123 Oxoglutarate/iron-dependent dioxygenase
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787