Basic information
Locus name	AT1G45145
Alias	ATTRX5/ATH5/LIV1/TRX5
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	LOCUS OF INSENSITIVITY TO VICTORIN 1, which encodes a cytosolic thioredoxin that reduces disulfide bridges of target proteins by the reversible formation of a disulfide bridge between two neighboring Cys residues present in the active site.; FUNCTIONS IN: oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; INVOLVED IN: response to oxidative stress, response to cadmium ion, defense response to fungus, response to microbial phytotoxin
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process cell redox homeostasis glycerol ether metabolic process molecular function electron carrier activity protein disulfide oxidoreductase activity
Sequence	AT1G45145.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126613	Accession Taxon NP_001078124 Arabidopsis thaliana NP_173403 Arabidopsis thaliana NP_175021 Arabidopsis thaliana NP_175128 ( AT1G45145 ) Arabidopsis thaliana NP_177146 Arabidopsis thaliana NP_177802 Arabidopsis thaliana NP_187483 Arabidopsis thaliana NP_188155 Arabidopsis thaliana NP_190672 Arabidopsis thaliana NP_192261 Arabidopsis thaliana NP_198811 Arabidopsis thaliana NP_199112 Arabidopsis thaliana NP_849585 Arabidopsis thaliana CMJ096C Cyanidioschyzon merolae strain 10D CMS271C Cyanidioschyzon merolae strain 10D CMV012C Cyanidioschyzon merolae strain 10D 134747 Chlamydomonas reinhardtii 136413 Chlamydomonas reinhardtii 195887 Chlamydomonas reinhardtii 196116 Chlamydomonas reinhardtii 196117 Chlamydomonas reinhardtii 196118 Chlamydomonas reinhardtii ACO64799 Micromonas sp. RCC299 ACO65470 Micromonas sp. RCC299 ACO68840 Micromonas sp. RCC299 NP_001045486 Oryza sativa Japonica Group NP_001047543 Oryza sativa Japonica Group NP_001051587 Oryza sativa Japonica Group NP_001053391 Oryza sativa Japonica Group NP_001055996 Oryza sativa Japonica Group NP_001059069 Oryza sativa Japonica Group NP_001059090 Oryza sativa Japonica Group e_gw1.01.00.680.1 Ostreococcus tauri e_gw1.05.00.532.1 Ostreococcus tauri e_gw1.10.00.417.1 Ostreococcus tauri gw1.03.00.565.1 Ostreococcus tauri gw1.17.00.275.1 Ostreococcus tauri e_gw1.106.97.1 Physcomitrella patens subsp. patens e_gw1.12.251.1 Physcomitrella patens subsp. patens e_gw1.136.116.1 Physcomitrella patens subsp. patens e_gw1.23.83.1 Physcomitrella patens subsp. patens e_gw1.317.34.1 Physcomitrella patens subsp. patens e_gw1.317.58.1 Physcomitrella patens subsp. patens e_gw1.326.22.1 Physcomitrella patens subsp. patens e_gw1.6.178.1 Physcomitrella patens subsp. patens e_gw1.98.209.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1060044 Physcomitrella patens subsp. patens estExt_Genewise1.C_210170 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_840217 Physcomitrella patens subsp. patens 29118.m000100 Ricinus communis 29648.m001915 Ricinus communis 29822.m003461 Ricinus communis 29863.m001051 Ricinus communis 29915.m000489 Ricinus communis 29983.m003200 Ricinus communis 30004.m000426 Ricinus communis 30170.m014109 Ricinus communis 35973.m000023 Ricinus communis e_gw1.22.202.1 Thalassiosira pseudonana CCMP1335 e_gw1.4.701.1 Thalassiosira pseudonana CCMP1335 e_gw1.4.706.1 Thalassiosira pseudonana CCMP1335 estExt_gwp_gw1.C_chr_40267 Thalassiosira pseudonana CCMP1335 estExt_gwp_gw1.C_chr_90074 Thalassiosira pseudonana CCMP1335 gw1.5.552.1 Thalassiosira pseudonana CCMP1335 gw1.5.553.1 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_20000004 Thalassiosira pseudonana CCMP1335 XP_002949006 Volvox carteri f. nagariensis XP_002949199 Volvox carteri f. nagariensis XP_002949687 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description ProSiteProfiles PS51352 14.2 1 113 IPR012336 Thioredoxin-like fold PANTHER PTHR10438 8.8E-41 4 111 IPR005746 Thioredoxin SUPERFAMILY SSF52833 1.9E-33 5 111 IPR012336 Thioredoxin-like fold Pfam PF00085 1.1E-29 9 111 IPR013766 Thioredoxin domain PIRSF PIRSF000077 6.7E-20 17 112 IPR005746 Thioredoxin PRINTS PR00421 3.5E-6 30 38 IPR005746 Thioredoxin ProSitePatterns PS00194 NA 31 49 IPR017937 Thioredoxin, conserved site PRINTS PR00421 3.5E-6 38 47 IPR005746 Thioredoxin PRINTS PR00421 3.5E-6 77 88 IPR005746 Thioredoxin
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787