Basic information
Locus name	AT1G04250
Alias	IAA17
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:IAA
Effect for Senescence	promote
Gene Description	INDOLE-3-ACETIC ACID INDUCIBLE 17 positively modulates natural leaf senescence through melatonin-mediated pathway in Arabidopsis.
Evidence	Genetic evidence [Ref 1]
References	1: Shi H, Reiter RJ, Tan DX, Chan Z. INDOLE-3-ACETIC ACID INDUCIBLE 17 positively modulates natural leaf senescence through melatonin-mediated pathway in Arabidopsis. J Pineal Res. 2015 Jan;58(1):26-33. doi: 10.1111/jpi.12188. Epub 2014 Nov 4.
Gene Ontology	biological process regulation of transcription, DNA-dependent cellular component nucleus molecular function protein dimerization activity
Sequence	AT1G04250.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name AtIAA17ox Mutant/Transgenic transgene Ecotype Col-0 Mutagenesis type transgenic
Mutated 2 Mutant name iaa17-1 (SALK_065697) Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA
Mutated 3 Mutant name iaa17-2 (SALK_011820) Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA
miRNA Interaction
Details	target: AT1G04250.1  miRNA: ath-miR847 miRNA: ath-miR847 mfe: -27.6 kcal/mol  p-value: 0.006396  position:  580  target 5' A   G          A   A   U 3'             CAU GAGGAGAAGA GGA UGA              GUA UUCUUCUUCU CCU ACU   miRNA  3'     G              C     5'
Ortholog Group
Ortholog Groups: OG5_144920	Accession Taxon NP_171921 ( AT1G04250 ) Arabidopsis thaliana NP_187124 Arabidopsis thaliana NP_188945 Arabidopsis thaliana NP_193191 Arabidopsis thaliana NP_974355 Arabidopsis thaliana NP_001043847 Oryza sativa Japonica Group NP_001051230 Oryza sativa Japonica Group NP_001056300 Oryza sativa Japonica Group NP_001067209 Oryza sativa Japonica Group estExt_Genewise1.C_1840013 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_730007 Physcomitrella patens subsp. patens 29598.m000460 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31734 7.1E-114 6 229 No hit NA Pfam PF02309 6.6E-85 7 221 IPR003311 AUX/IAA protein SUPERFAMILY SSF54277 1.9E-19 108 210 No hit NA ProSiteProfiles PS50962 29.6 111 212 IPR011525 Aux/IAA-ARF-dimerisation
Mutant Image
AtIAA17-overexpressing plants showed early leaf senescence with lower chlorophyll content in rosette leaves compared with wild-type plants, while AtIAA17 knockout mutants displayed delayed leaf senescence with higher chlorophyll content
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787