Basic information
Locus name	AT1G50460
Alias	HKL1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction (sucrose)
Effect for Senescence	unclear
Gene Description	HEXOKINASE-LIKE 1 (HKL1); FUNCTIONS IN: hexokinase activity, fructokinase activity, glucokinase activity, ATP binding; INVOLVED IN: response to salt stress, response to cold, response to osmotic stress
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process carbohydrate metabolic process molecular function ATP binding phosphotransferase activity, alcohol group as acceptor
Pathway	KEGG map00010 (EC 2.7.1.1) map00051 (EC 2.7.1.1) map00052 (EC 2.7.1.1) map00500 (EC 2.7.1.1) map00520 (EC 2.7.1.1) map00521 (EC 2.7.1.1) map00524 (EC 2.7.1.1) MetaCyc PWY-621 PWY-6531
Sequence	AT1G50460.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT1G50460.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -32.1 kcal/mol  p-value: 0.000706  position: 202  target 5' A U                  U  3'             G UGAUGAUGAUGAAGAUGG                 C GCUACUACUACUUCUACU      miRNA  3' A U                     5'
Ortholog Group
Ortholog Groups: OG5_176520	Accession Taxon NP_175463 ( AT1G50460 ) Arabidopsis thaliana NP_188639 Arabidopsis thaliana NP_001055376 Oryza sativa Japonica Group 30169.m006483 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description ProSiteProfiles PS51257 5.0 1 17 No hit NA PANTHER PTHR19443 5.3E-220 21 494 IPR001312 Hexokinase SUPERFAMILY SSF53067 2.2E-62 23 241 No hit NA Pfam PF00349 2.5E-51 38 239 IPR022672 Hexokinase, N-terminal PRINTS PR00475 4.0E-52 98 114 IPR001312 Hexokinase PRINTS PR00475 4.0E-52 171 196 IPR001312 Hexokinase PRINTS PR00475 4.0E-52 223 239 IPR001312 Hexokinase SUPERFAMILY SSF53067 6.6E-72 243 495 No hit NA Pfam PF03727 8.9E-57 244 494 IPR022673 Hexokinase, C-terminal PRINTS PR00475 4.0E-52 246 260 IPR001312 Hexokinase PRINTS PR00475 4.0E-52 311 333 IPR001312 Hexokinase PRINTS PR00475 4.0E-52 392 414 IPR001312 Hexokinase
Subcellular Localization
Localization 1 Localization mitochondria Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization mitochondrion Evidence SUBAcon Pubmed ID 23180787