Basic information
Locus name	AT1G64740
Alias	TUA1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others(cytoskeleton)
Effect for Senescence	unclear
Gene Description	ALPHA-1 TUBULIN (TUA1); FUNCTIONS IN: structural constituent of cytoskeleton; INVOLVED IN: microtubule-based process; LOCATED IN: cytosol, microtubule cytoskeleton, plasma membrane
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process microtubule-based process cellular component microtubule molecular function GTP binding
Pathway	Reactome REACT_152
Sequence	AT1G64740.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126605	Accession Taxon NP_171974 Arabidopsis thaliana NP_175423 Arabidopsis thaliana NP_176654 ( AT1G64740 ) Arabidopsis thaliana NP_193232 Arabidopsis thaliana NP_197478 Arabidopsis thaliana NP_197479 Arabidopsis thaliana NP_849388 Arabidopsis thaliana CMT504C Cyanidioschyzon merolae strain 10D 128523 Chlamydomonas reinhardtii 186023 Chlamydomonas reinhardtii NP_113413 Guillardia theta ACO67325 Micromonas sp. RCC299 ACO69268 Micromonas sp. RCC299 NP_001049400 Oryza sativa Japonica Group NP_001051132 Oryza sativa Japonica Group NP_001060075 Oryza sativa Japonica Group NP_001067613 Oryza sativa Japonica Group estExt_fgenesh1_pm.C_Chr_12.00010025 Ostreococcus tauri fgenesh1_pm.C_Chr_08.0001000046 Ostreococcus tauri e_gw1.11.3.1 Physcomitrella patens subsp. patens e_gw1.131.6.1 Physcomitrella patens subsp. patens e_gw1.215.113.1 Physcomitrella patens subsp. patens e_gw1.48.5.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_3410014 Physcomitrella patens subsp. patens estExt_Genewise1.C_3410020 Physcomitrella patens subsp. patens estExt_Genewise1.C_700139 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_2150009 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_335000037 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_5000108 Physcomitrella patens subsp. patens 29822.m003495 Ricinus communis 29950.m001120 Ricinus communis 30084.m000186 Ricinus communis 30099.m001691 Ricinus communis 30170.m013630 Ricinus communis estExt_Genewise1.C_chr_90079 Thalassiosira pseudonana CCMP1335 XP_002951007 Volvox carteri f. nagariensis XP_002957217 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11588 0.0 1 450 IPR000217 Tubulin ProSitePatterns PS00228 NA 1 4 IPR013838 Beta tubulin, autoregulation binding site SUPERFAMILY SSF52490 6.7E-97 1 244 IPR003008 Tubulin/FtsZ, GTPase domain Pfam PF00091 1.3E-70 3 225 IPR003008 Tubulin/FtsZ, GTPase domain PRINTS PR01161 7.6E-89 10 30 IPR000217 Tubulin PRINTS PR01162 8.0E-111 18 33 IPR002452 Alpha tubulin PRINTS PR01162 8.0E-111 45 58 IPR002452 Alpha tubulin SMART SM00864 1.4E-71 49 246 IPR003008 Tubulin/FtsZ, GTPase domain PRINTS PR01161 7.6E-89 53 72 IPR000217 Tubulin PRINTS PR01162 8.0E-111 88 101 IPR002452 Alpha tubulin PRINTS PR01161 7.6E-89 95 106 IPR000217 Tubulin PRINTS PR01161 7.6E-89 108 132 IPR000217 Tubulin PRINTS PR01162 8.0E-111 120 128 IPR002452 Alpha tubulin PRINTS PR01161 7.6E-89 134 152 IPR000217 Tubulin ProSitePatterns PS00227 NA 142 148 IPR017975 Tubulin, conserved site PRINTS PR01162 8.0E-111 148 160 IPR002452 Alpha tubulin PRINTS PR01161 7.6E-89 153 174 IPR000217 Tubulin PRINTS PR01162 8.0E-111 161 172 IPR002452 Alpha tubulin PRINTS PR01161 7.6E-89 178 191 IPR000217 Tubulin PRINTS PR01161 7.6E-89 192 212 IPR000217 Tubulin PRINTS PR01162 8.0E-111 214 226 IPR002452 Alpha tubulin SUPERFAMILY SSF55307 3.4E-85 246 436 IPR008280 Tubulin/FtsZ, C-terminal SMART SM00865 3.3E-52 248 393 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Pfam PF03953 6.5E-51 263 393 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain PRINTS PR01162 8.0E-111 274 289 IPR002452 Alpha tubulin PRINTS PR01162 8.0E-111 321 342 IPR002452 Alpha tubulin PRINTS PR01162 8.0E-111 347 360 IPR002452 Alpha tubulin PRINTS PR01162 8.0E-111 360 379 IPR002452 Alpha tubulin PRINTS PR01161 7.6E-89 380 408 IPR000217 Tubulin PRINTS PR01162 8.0E-111 385 401 IPR002452 Alpha tubulin Coils Coil NA 418 439 No hit NA PRINTS PR01162 8.0E-111 422 438 IPR002452 Alpha tubulin
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787