Basic information
Locus name	AT1G75950
Alias	SKP1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	S PHASE KINASE-ASSOCIATED PROTEIN 1 (SKP1); FUNCTIONS IN: ubiquitin-protein ligase activity, protein binding; INVOLVED IN: negative regulation of DNA recombination, response to cadmium ion, mitosis, ubiquitin-dependent protein catabolic process, male meiosis
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process ubiquitin-dependent protein catabolic process
Pathway	Reactome REACT_6185
Sequence	AT1G75950.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127430	Accession Taxon NP_565123 ( AT1G75950 ) Arabidopsis thaliana NP_567090 Arabidopsis thaliana NP_567959 Arabidopsis thaliana NP_567967 Arabidopsis thaliana NP_568603 Arabidopsis thaliana CMP118C Cyanidioschyzon merolae strain 10D 128004 Chlamydomonas reinhardtii ACO65881 Micromonas sp. RCC299 NP_001058882 Oryza sativa Japonica Group NP_001061672 Oryza sativa Japonica Group NP_001062743 Oryza sativa Japonica Group NP_001062746 Oryza sativa Japonica Group NP_001062747 Oryza sativa Japonica Group NP_001063805 Oryza sativa Japonica Group fgenesh1_pg.C_Chr_20.0001000042 Ostreococcus tauri estExt_fgenesh1_pg.C_90170 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_70040 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_49000019 Physcomitrella patens subsp. patens 28962.m000447 Ricinus communis 30170.m014264 Ricinus communis 30170.m014265 Ricinus communis 34425.m000015 Ricinus communis e_gw1.20.162.1 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_15000067 Thalassiosira pseudonana CCMP1335 XP_002947872 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11165 7.4E-103 1 160 IPR001232 SKP1 component PIRSF PIRSF028729 2.7E-79 1 160 IPR016897 E3 ubiquitin ligase, SCF complex, Skp subunit SMART SM00512 3.4E-56 3 110 IPR001232 SKP1 component Pfam PF03931 1.9E-27 4 63 IPR016073 SKP1 component, POZ SUPERFAMILY SSF54695 2.1E-20 5 64 IPR011333 BTB/POZ fold Pfam PF01466 1.3E-41 83 160 IPR016072 SKP1 component, dimerisation SUPERFAMILY SSF81382 3.4E-32 83 158 IPR016072 SKP1 component, dimerisation
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization cytosol Evidence SUBAcon Pubmed ID 23180787