Basic information
Locus name	At5G13080
Alias	AtWRKY75
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category
Effect for Senescence	promote
Gene Description	WRKY57 was shown to function as a common component of JA- and auxin-mediated signaling pathways to modulate JA-induced leaf senescence . In addition, WRKY75, together with SA and reactive oxygen species (ROS), has been shown to form a tripartite amplification loop to promote leaf senescence . AtWRKY75 positively regulates age-triggered leaf senescence through gibberellin pathway.
Evidence	Genetic evidence [Ref 1]
References	1: Zhang H, Zhang L, Wu S, Chen Y, Yu D, Chen L. AtWRKY75 positively regulates age-triggered leaf senescence through gibberellin pathway Plant Divers. 2020 Nov 1;43(4):331-340. doi: 10.1016/j.pld.2020.10.002. eCollection 2021 Aug.
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function sequence-specific DNA binding transcription factor activity sequence-specific DNA binding
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_178045	Accession Taxon NP_196812 ( At5G13080 ) Arabidopsis thaliana NP_001067928 Oryza sativa Japonica Group 29929.m004624 Ricinus communis 30190.m010908 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31221 6.4E-32 54 125 No hit NA SUPERFAMILY SSF118290 6.9E-29 58 125 IPR003657 DNA-binding WRKY ProSiteProfiles PS50811 29.8 61 126 IPR003657 DNA-binding WRKY Pfam PF03106 5.8E-30 66 124 IPR003657 DNA-binding WRKY SMART SM00774 1.9E-37 66 125 IPR003657 DNA-binding WRKY
Mutant Image
wrky75 mutant exhibited delay senescence.
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787