Basic information
Locus name	AT1G73980
Alias	TTM1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category
Effect for Senescence	promote
Gene Description	ABA-induced senescence is delayed in ttm1.Multiple phosphorylation events of the mitochondrial membrane protein TTM1 regulate cell death during senescence
Evidence	Genetic evidence [Ref 1]
References	1:
Gene Ontology	molecular function ATP binding phosphotransferase activity, alcohol group as acceptor uridine kinase activity
Pathway	KEGG map00240 (EC 2.7.1.48) map00983 (EC 2.7.1.48)
Mutant information
Mutant name	ttm1
Mutant/Transgenic
Ecotype	Col-0
Mutagenesis type	T-DNA
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_150260	Accession Taxon NP_173944 Arabidopsis thaliana NP_177538 ( AT1G73980 ) Arabidopsis thaliana 147285 Chlamydomonas reinhardtii ACO66573 Micromonas sp. RCC299 NP_001047881 Oryza sativa Japonica Group e_gw1.15.00.52.1 Ostreococcus tauri 30138.m003855 Ricinus communis 30174.m009044 Ricinus communis XP_002949935 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10285 6.2E-258 1 497 No hit NA SUPERFAMILY SSF52540 3.8E-21 63 236 IPR027417 P-loop containing nucleoside triphosphate hydrolase PRINTS PR00988 8.1E-11 65 82 IPR000764 Uridine kinase Pfam PF00485 4.9E-22 68 236 IPR006083 Phosphoribulokinase/uridine kinase PRINTS PR00988 8.1E-11 132 147 IPR000764 Uridine kinase PRINTS PR00988 8.1E-11 188 198 IPR000764 Uridine kinase PRINTS PR00988 8.1E-11 224 237 IPR000764 Uridine kinase Pfam PF01928 3.3E-20 262 409 IPR023577 CYTH-like domain SUPERFAMILY SSF55154 9.2E-16 270 407 IPR023577 CYTH-like domain Coils Coil NA 500 528 No hit NA
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787