Basic information
Locus name	AT1G11190
Alias	ENDO1/BFN1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category
Effect for Senescence	promote
Gene Description	The increased expression of ENDO1 accelerates senescence
Evidence	Genetic evidence [Ref 1]
References	1:
Gene Ontology	biological process DNA catabolic process molecular function endonuclease activity hydrolase activity, acting on ester bonds nucleic acid binding
Mutant information
Mutant name	BFN1-OE
Mutant/Transgenic
Ecotype	Col-0
Mutagenesis type	transgene
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT1G11190.1  miRNA: ath-miR156a miRNA: ath-miR156a mfe: -30.9 kcal/mol  p-value: 0.001575  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           U 5'  target: AT1G11190.1  miRNA: ath-miR156b miRNA: ath-miR156b mfe: -30.9 kcal/mol  p-value: 0.001155  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           U 5'  target: AT1G11190.1  miRNA: ath-miR156c miRNA: ath-miR156c mfe: -30.9 kcal/mol  p-value: 0.001516  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           U 5'  target: AT1G11190.1  miRNA: ath-miR156d miRNA: ath-miR156d mfe: -30.9 kcal/mol  p-value: 0.001665  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           U 5'  target: AT1G11190.1  miRNA: ath-miR156e miRNA: ath-miR156e mfe: -30.9 kcal/mol  p-value: 0.001065  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           U 5'  target: AT1G11190.1  miRNA: ath-miR156f miRNA: ath-miR156f mfe: -30.9 kcal/mol  p-value: 0.001585  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           U 5'  target: AT1G11190.1  miRNA: ath-miR156g miRNA: ath-miR156g mfe: -31.2 kcal/mol  p-value: 0.000873  position:  143  target 5' U       G           C 3'             GUGUUCG UUUCUUCUGUC              CACGAGU AGAGAAGACAG   miRNA  3'         G           C 5'
Ortholog Group
Ortholog Groups: OG5_128720	Accession Taxon NP_001078420 Arabidopsis thaliana NP_172585 ( AT1G11190 ) Arabidopsis thaliana NP_176996 Arabidopsis thaliana NP_567630 Arabidopsis thaliana NP_567631 Arabidopsis thaliana NP_680734 Arabidopsis thaliana NP_001041909 Oryza sativa Japonica Group NP_001041910 Oryza sativa Japonica Group NP_001054017 Oryza sativa Japonica Group NP_001054101 Oryza sativa Japonica Group gw1.211.34.1 Physcomitrella patens subsp. patens 29917.m001957 Ricinus communis 29917.m001958 Ricinus communis 30066.m000708 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR32188 1.3E-118 4 305 No hit NA Pfam PF02265 8.4E-81 29 294 IPR003154 S1/P1 nuclease SUPERFAMILY SSF48537 1.8E-77 29 291 IPR008947 Phospholipase C/P1 nuclease domain Coils Coil NA 197 218 No hit NA
Subcellular Localization
Localization	extracellular
Evidence	SUBAcon
Pubmed ID	23180787