Basic information
Locus name	AT2G17420
Alias	NTRA
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	NADPH-DEPENDENT THIOREDOXIN REDUCTASE A (NTRA); FUNCTIONS IN: thioredoxin-disulfide reductase activity
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function oxidoreductase activity
Pathway	KEGG map00240 (EC 1.8.1.9)
Sequence	AT2G17420.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127532	Accession Taxon NP_179334 ( AT2G17420 ) Arabidopsis thaliana NP_195271 Arabidopsis thaliana NP_565954 Arabidopsis thaliana CMI298C Cyanidioschyzon merolae strain 10D 132865 Chlamydomonas reinhardtii 78928 Chlamydomonas reinhardtii ACO61909 Micromonas sp. RCC299 NP_001047911 Oryza sativa Japonica Group NP_001057531 Oryza sativa Japonica Group NP_001060515 Oryza sativa Japonica Group gw1.18.00.54.1 Ostreococcus tauri e_gw1.8.97.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_4550002 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_80153 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_90055 Physcomitrella patens subsp. patens 29363.m000070 Ricinus communis 29682.m000572 Ricinus communis 30006.m000289 Ricinus communis estExt_gwp_gw1.C_chr_40101 Thalassiosira pseudonana CCMP1335 XP_002948592 Volvox carteri f. nagariensis XP_002956971 Volvox carteri f. nagariensis XP_002956989 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR22912 8.3E-129 49 369 No hit NA SUPERFAMILY SSF51905 8.9E-44 49 367 No hit NA Pfam PF07992 1.9E-24 55 345 IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain PRINTS PR00469 1.2E-75 55 77 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II TIGRFAM TIGR01292 2.7E-115 55 367 IPR005982 Thioredoxin reductase PRINTS PR00368 1.1E-32 56 75 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00469 1.2E-75 93 108 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II PRINTS PR00469 1.2E-75 114 124 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II PRINTS PR00368 1.1E-32 158 176 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00469 1.2E-75 159 167 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II PRINTS PR00469 1.2E-75 185 197 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II ProSitePatterns PS00573 NA 192 214 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site PRINTS PR00469 1.2E-75 202 226 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II PRINTS PR00368 1.1E-32 206 224 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfam PF00070 2.5E-16 207 274 IPR001327 Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain PRINTS PR00469 1.2E-75 254 270 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II PRINTS PR00368 1.1E-32 293 309 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00469 1.2E-75 295 316 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II PRINTS PR00368 1.1E-32 320 342 IPR013027 FAD-dependent pyridine nucleotide-disulphide oxidoreductase PRINTS PR00469 1.2E-75 330 348 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II
Subcellular Localization
Localization 1 Localization cytosol Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization cytosol Evidence SUBAcon Pubmed ID 23180787