Basic information
Locus name	AT2G17520
Alias	IRE1A
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	IRE1A; FUNCTIONS IN: endoribonuclease activity, kinase activity; INVOLVED IN: activation of signaling protein activity involved in unfolded protein response
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process mRNA processing protein phosphorylation molecular function ATP binding protein kinase activity protein serine/threonine kinase activity ribonuclease activity
Sequence	AT2G17520.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_128843	Accession Taxon NP_565419 ( AT2G17520 ) Arabidopsis thaliana NP_568444 Arabidopsis thaliana CMM326C Cyanidioschyzon merolae strain 10D 20714 Chlamydomonas reinhardtii ACO63695 Micromonas sp. RCC299 NP_001059606 Oryza sativa Japonica Group gw1.02.00.438.1 Ostreococcus tauri e_gw1.34.151.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_650039 Physcomitrella patens subsp. patens 29830.m001467 Ricinus communis e_gw1.12.159.1 Thalassiosira pseudonana CCMP1335 XP_002958109 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13954 0.0 235 841 No hit NA ProSiteProfiles PS50011 36.8 414 704 IPR000719 Protein kinase, catalytic domain SMART SM00220 6.8E-34 414 704 IPR002290 Serine/threonine- / dual specificity protein kinase, catalytic domain SUPERFAMILY SSF56112 3.1E-58 414 497 IPR011009 Protein kinase-like domain Pfam PF00069 1.0E-40 417 704 IPR000719 Protein kinase, catalytic domain SUPERFAMILY SSF56112 3.1E-58 538 709 IPR011009 Protein kinase-like domain ProSitePatterns PS00108 NA 566 578 IPR008271 Serine/threonine-protein kinase, active site ProSiteProfiles PS51392 39.3 707 838 IPR010513 KEN domain Pfam PF06479 9.9E-46 710 837 IPR010513 KEN domain SMART SM00580 1.6E-23 769 823 IPR006567 PUG domain
Subcellular Localization
Localization 1 Localization ER Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization endoplasmic reticulum Evidence SUBAcon Pubmed ID 23180787