Basic information
Locus name	AT2G26300
Alias	GP ALPHA 1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	G PROTEIN ALPHA SUBUNIT 1 (GP ALPHA 1); FUNCTIONS IN: GTP binding, channel regulator activity, GTPase activity, signal transducer activity
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process G-protein coupled receptor signaling pathway molecular function G-protein beta/gamma-subunit complex binding GTPase activity guanyl nucleotide binding signal transducer activity
Pathway	Reactome REACT_14797
Sequence	AT2G26300.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT2G26300.1  miRNA: ath-miR5021 miRNA: ath-miR5021 mfe: -30.4 kcal/mol  p-value: 0.000065  position: 390  target 5' C                  C  3'             UUUCUUCUUCUUCUUCUU                 AAAGAAGAAGAAGAAGAG      miRNA  3' A                  U  5'
Ortholog Group
Ortholog Groups: OG5_126802	Accession Taxon NP_180198 ( AT2G26300 ) Arabidopsis thaliana NP_001055226 Oryza sativa Japonica Group 29739.m003634 Ricinus communis e_gw1.9.102.1 Thalassiosira pseudonana CCMP1335
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10218 5.4E-287 1 383 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit Pfam PF00503 7.6E-110 9 382 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit SMART SM00275 4.5E-155 18 382 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit PRINTS PR01242 5.7E-60 26 35 IPR002976 Plant G-protein, alpha subunit SUPERFAMILY SSF52540 1.4E-45 35 62 IPR027417 P-loop containing nucleoside triphosphate hydrolase PRINTS PR00318 9.0E-49 40 55 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit SUPERFAMILY SSF47895 8.0E-31 66 191 IPR011025 G protein alpha subunit, helical insertion PRINTS PR01242 5.7E-60 76 89 IPR002976 Plant G-protein, alpha subunit PRINTS PR01242 5.7E-60 91 105 IPR002976 Plant G-protein, alpha subunit PRINTS PR01242 5.7E-60 115 129 IPR002976 Plant G-protein, alpha subunit PRINTS PR00318 9.0E-49 179 201 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit SUPERFAMILY SSF52540 1.4E-45 186 380 IPR027417 P-loop containing nucleoside triphosphate hydrolase PRINTS PR01242 5.7E-60 199 214 IPR002976 Plant G-protein, alpha subunit PRINTS PR00318 9.0E-49 214 231 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit PRINTS PR00318 9.0E-49 236 264 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit PRINTS PR01242 5.7E-60 269 280 IPR002976 Plant G-protein, alpha subunit PRINTS PR00318 9.0E-49 282 291 IPR001019 Guanine nucleotide binding protein (G-protein), alpha subunit PRINTS PR01242 5.7E-60 318 333 IPR002976 Plant G-protein, alpha subunit PRINTS PR01242 5.7E-60 335 347 IPR002976 Plant G-protein, alpha subunit
Subcellular Localization
Localization 1 Localization ER Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization plasma membrane Evidence SUBAcon Pubmed ID 23180787