Basic information
Locus name	AT3G12490
Alias	ATCYSB
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:endopeptidase inhibitor
Effect for Senescence	unclear
Gene Description	CYSTATIN B (ATCYSB); FUNCTIONS IN: cysteine-type endopeptidase inhibitor activity; INVOLVED IN: response to abiotic stimulus; LOCATED IN: endomembrane system
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	molecular function cysteine-type endopeptidase inhibitor activity
Sequence	AT3G12490.1 | Genomic | mRNA | CDS | Protein AT3G12490.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_156637	Accession Taxon NP_566425 Arabidopsis thaliana NP_850570 ( AT3G12490 ) Arabidopsis thaliana NP_001042702 Oryza sativa Japonica Group e_gw1.212.78.1 Physcomitrella patens subsp. patens e_gw1.66.151.1 Physcomitrella patens subsp. patens estExt_fgenesh1_kg.C_2380002 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2380025 Physcomitrella patens subsp. patens 29686.m000868 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11413 3.9E-70 2 136 IPR027214 Cystatin SUPERFAMILY SSF54403 2.3E-30 33 126 No hit NA SMART SM00043 7.1E-32 35 125 IPR000010 Proteinase inhibitor I25, cystatin Pfam PF00031 6.4E-16 43 124 IPR000010 Proteinase inhibitor I25, cystatin ProSitePatterns PS00287 NA 81 94 IPR018073 Proteinase inhibitor I25, cystatin, conserved site SUPERFAMILY SSF54403 4.5E-15 137 222 No hit NA Pfam PF00031 2.5E-6 146 223 IPR000010 Proteinase inhibitor I25, cystatin
Subcellular Localization
Localization 1 Localization cytosol Evidence SUBAcon Pubmed ID 23180787
Localization 2 Localization extracellular Evidence SUBAcon Pubmed ID 23180787