Basic information
GenBank ID	DQ869673
Alias	NAM-B1
Organism	Wheat (Triticum turgidum)
Taxonomic identifier	[NCBI]
Function category	Transcriptional regulation:NAC
Effect for Senescence	promote
Gene Description	NAM-B1 encodes a NAC transcription factor (NAM-B1) that accelerates senescence and increases nutrient remobilization from leaves to developing grains, whereas modern wheat varieties carry a nonfunctional NAM-B1 allele. Reduction in RNA levels of the multiple NAM homologs by RNA interference delayed senescence by more than 3 weeks and reduced wheat grain protein, zinc, and iron content by more than 30%.
Evidence	Genetic evidence:Transgene and mutant [Ref 1, Ref 2]
References	1: Uauy C, Distelfeld A, Fahima T, Blechl A, Dubcovsky J A NAC Gene regulating senescence improves grain protein, zinc, and iron content in wheat. Science 2006 Nov 24;314(5803):1298-301 2: Uauy C, Brevis JC, Dubcovsky J The high grain protein content gene Gpc-B1 accelerates senescence and has pleiotropic effects on protein content in wheat. J. Exp. Bot. 2006;57(11):2785-94
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function DNA binding
Sequence	DQ869673.1 | mRNA | CDS | Protein
Mutant information
Mutant name	NtNAM-B1_RNAi
Mutant/Transgenic	transgenic
Ecotype	Wheat (Triticum turgidum subsp)
Mutagenesis type	RNAi
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31719 1.5E-110 18 207 No hit NA SUPERFAMILY SSF101941 1.4E-61 31 205 IPR003441 No apical meristem (NAM) protein Pfam PF02365 7.1E-51 34 166 IPR003441 No apical meristem (NAM) protein ProSiteProfiles PS51005 60.1 34 205 IPR003441 No apical meristem (NAM) protein