Basic information
Locus name	AT2G02990
Alias	RNS1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Nucleic acid degradation:Ribonuclease
Effect for Senescence	Unclear
Gene Description	Ribonuclease 1 (RNS1).Upregulated in senescent leaves.
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	molecular function RNA binding ribonuclease T2 activity
Sequence	AT2G02990.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
miRNA Interaction
Details	target: AT2G02990.1  miRNA: ath-miR395a miRNA: ath-miR395a mfe: -26.9 kcal/mol  p-value: 0.011034  position:  522  target 5' U  C  G        G     G 3'             GG UU CCCAAGCG UUCAG              UC AG GGGUUUGU AAGUC   miRNA  3' C  A  G        G       5'  target: AT2G02990.1  miRNA: ath-miR395d miRNA: ath-miR395d mfe: -26.9 kcal/mol  p-value: 0.014826  position:  522  target 5' U  C  G        G     G 3'             GG UU CCCAAGCG UUCAG              UC AG GGGUUUGU AAGUC   miRNA  3' C  A  G        G       5'  target: AT2G02990.1  miRNA: ath-miR395e miRNA: ath-miR395e mfe: -26.9 kcal/mol  p-value: 0.012355  position:  522  target 5' U  C  G        G     G 3'             GG UU CCCAAGCG UUCAG              UC AG GGGUUUGU AAGUC   miRNA  3' C  A  G        G       5'
Ortholog Group
Ortholog Groups: OG5_128552	Accession Taxon NP_001118478 Arabidopsis thaliana NP_030524 Arabidopsis thaliana NP_178399 ( AT2G02990 ) Arabidopsis thaliana 115231 Chlamydomonas reinhardtii NP_001045086 Oryza sativa Japonica Group NP_001045087 Oryza sativa Japonica Group NP_001061877 Oryza sativa Japonica Group e_gw1.358.41.1 Physcomitrella patens subsp. patens e_gw1.59.205.1 Physcomitrella patens subsp. patens 29813.m001494 Ricinus communis 29813.m001495 Ricinus communis 30005.m001265 Ricinus communis XP_002946824 Volvox carteri f. nagariensis XP_002947011 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11240 2.1E-79 1 230 IPR001568 Ribonuclease T2-like SUPERFAMILY SSF55895 1.4E-74 26 229 IPR001568 Ribonuclease T2-like Pfam PF00445 1.3E-60 30 214 IPR001568 Ribonuclease T2-like ProSitePatterns PS00530 NA 62 69 IPR018188 Ribonuclease T2, active site ProSitePatterns PS00531 NA 115 126 IPR018188 Ribonuclease T2, active site
Subcellular Localization
Localization 1 Localization extracellular Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization extracellular Evidence SUBAcon Pubmed ID 23180787