Basic information
Locus name	AT3G45590
Alias	ATSEN
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	SPLICING ENDONUCLEASE 1 (ATSEN1); FUNCTIONS IN: tRNA-intron endonuclease activity, nuclease activity, nucleic acid binding; INVOLVED IN: tRNA splicing, via endonucleolytic cleavage and ligation; LOCATED IN: tRNA-intron endonuclease complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages;
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process tRNA splicing, via endonucleolytic cleavage and ligation molecular function tRNA-intron endonuclease activity
Sequence	AT3G45590.1 | Genomic | mRNA | CDS | Protein AT3G45590.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_128736	Accession Taxon NP_001078245 ( AT3G45590 ) Arabidopsis thaliana NP_190145 Arabidopsis thaliana NP_200831 Arabidopsis thaliana NP_974966 Arabidopsis thaliana CMN231C Cyanidioschyzon merolae strain 10D 166960 Chlamydomonas reinhardtii NP_113457 Guillardia theta ACO68378 Micromonas sp. RCC299 NP_001057781 Oryza sativa Japonica Group NP_001068231 Oryza sativa Japonica Group estExt_fgenesh1_pg.C_Chr_12.00010165 Ostreococcus tauri e_gw1.54.129.1 Physcomitrella patens subsp. patens 30111.m000699 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR21227 2.1E-78 1 236 No hit NA Pfam PF02778 1.5E-16 37 108 IPR006678 tRNA intron endonuclease, N-terminal SUPERFAMILY SSF53032 2.3E-25 117 202 IPR006677 tRNA intron endonuclease, catalytic domain-like Pfam PF01974 2.7E-24 118 200 IPR006677 tRNA intron endonuclease, catalytic domain-like
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787