Basic information
Locus name	AT5G20010
Alias	RAN-1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	signal transduction
Effect for Senescence	unclear
Gene Description	RAN-1; FUNCTIONS IN: protein binding, GTP binding, GTPase activity; INVOLVED IN: response to cadmium ion, response to salt stress, protein import into nucleus; LOCATED IN: apoplast, cell wall, plasma membrane;
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process GTP catabolic process intracellular protein transport nucleocytoplasmic transport signal transduction molecular function GTP binding GTPase activity
Pathway	Reactome REACT_11044
Sequence	AT5G20010.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127514	Accession Taxon NP_197501 ( AT5G20010 ) Arabidopsis thaliana NP_197502 Arabidopsis thaliana NP_200330 Arabidopsis thaliana CMT257C Cyanidioschyzon merolae strain 10D 128522 Chlamydomonas reinhardtii NP_113408 Guillardia theta ACO64559 Micromonas sp. RCC299 NP_001043550 Oryza sativa Japonica Group NP_001056390 Oryza sativa Japonica Group e_gw1.13.00.293.1 Ostreococcus tauri e_gw1.10.215.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_2580074 Physcomitrella patens subsp. patens estExt_Genewise1.C_290081 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_440063 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_440211 Physcomitrella patens subsp. patens fgenesh1_pm.scaffold_10000033 Physcomitrella patens subsp. patens 29848.m004668 Ricinus communis estExt_gwp_gw1.C_chr_20244 Thalassiosira pseudonana CCMP1335 XP_002957219 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24071 3.3E-183 1 221 No hit NA ProSiteProfiles PS51418 25.7 7 171 IPR002041 Ran GTPase SMART SM00173 5.8E-18 11 174 IPR020849 Small GTPase superfamily, Ras type SMART SM00175 2.0E-27 14 174 IPR003579 Small GTPase superfamily, Rab type SUPERFAMILY SSF52540 6.3E-49 14 191 IPR027417 P-loop containing nucleoside triphosphate hydrolase TIGRFAM TIGR00231 6.4E-25 14 164 IPR005225 Small GTP-binding protein domain Pfam PF00071 3.8E-50 15 171 IPR001806 Small GTPase superfamily SMART SM00174 1.2E-8 16 170 IPR003578 Small GTPase superfamily, Rho type SMART SM00176 1.6E-166 19 220 IPR002041 Ran GTPase PRINTS PR00627 7.8E-61 27 41 IPR002041 Ran GTPase PRINTS PR00627 7.8E-61 74 92 IPR002041 Ran GTPase PRINTS PR00627 7.8E-61 94 115 IPR002041 Ran GTPase PRINTS PR00627 7.8E-61 130 148 IPR002041 Ran GTPase PRINTS PR00627 7.8E-61 168 190 IPR002041 Ran GTPase
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787