Basic information
Locus name	AT5G64070
Alias	PI-4KBETA1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	PHOSPHATIDYLINOSITOL 4-OH KINASE BETA1 (PI-4KBETA1); FUNCTIONS IN: 1-phosphatidylinositol 4-kinase activity; INVOLVED IN: phosphoinositide biosynthetic process, root hair cell tip growth, pollen tube growth; LOCATED IN: cytosol, nucleus, membrane; EXPRESSED IN: root hair tip, male gametophyte, cultured cell, pollen tube;
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process phosphatidylinositol phosphorylation phosphatidylinositol-mediated signaling molecular function phosphotransferase activity, alcohol group as acceptor
Sequence	AT5G64070.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127682	Accession Taxon NP_196497 Arabidopsis thaliana NP_201212 ( AT5G64070 ) Arabidopsis thaliana CMI125C Cyanidioschyzon merolae strain 10D CMS267C Cyanidioschyzon merolae strain 10D 196944 Chlamydomonas reinhardtii ACO67616 Micromonas sp. RCC299 NP_001067479 Oryza sativa Japonica Group e_gw1.16.00.189.1 Ostreococcus tauri e_gw1.263.2.1 Physcomitrella patens subsp. patens estExt_fgenesh2_pm.C_1130010 Physcomitrella patens subsp. patens 30136.m001047 Ricinus communis e_gw1.1.251.1 Thalassiosira pseudonana CCMP1335 estExt_Genewise1.C_chr_70414 Thalassiosira pseudonana CCMP1335 XP_002947468 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description ProSiteProfiles PS51545 12.0 1 143 IPR001263 Phosphoinositide 3-kinase, accessory (PIK) domain PANTHER PTHR10048 6.4E-201 49 1121 IPR015433 Phosphatidylinositol Kinase SUPERFAMILY SSF48371 1.8E-6 57 128 IPR016024 Armadillo-type fold SUPERFAMILY SSF56112 2.2E-84 577 639 IPR011009 Protein kinase-like domain SUPERFAMILY SSF56112 2.2E-84 851 1114 IPR011009 Protein kinase-like domain ProSiteProfiles PS50290 57.8 859 1121 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain Pfam PF00454 3.7E-29 860 1062 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain SMART SM00146 2.1E-89 860 1119 IPR000403 Phosphatidylinositol 3-/4-kinase, catalytic domain ProSitePatterns PS00915 NA 863 877 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site ProSitePatterns PS00916 NA 957 977 IPR018936 Phosphatidylinositol 3/4-kinase, conserved site
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization nucleus Evidence Localization with GFP-ORF fusion protein (GFP:cDNA) Pubmed ID 15610358
Localization 3 Localization cytosol Evidence SUBAcon Pubmed ID 23180787