Basic information
Locus name	AT3G61530
Alias	PANB2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	PANB2; FUNCTIONS IN: 3-methyl-2-oxobutanoate hydroxymethyltransferase activity; INVOLVED IN: pantothenate biosynthetic process; LOCATED IN: mitochondrion;
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process pantothenate biosynthetic process molecular function 3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Pathway	KEGG map00770 (EC 2.1.2.11) MetaCyc PWY-6654
Sequence	AT3G61530.1 | Genomic | mRNA | CDS | Protein AT3G61530.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_129046	Accession Taxon NP_182135 Arabidopsis thaliana NP_191712 Arabidopsis thaliana NP_974474 ( AT3G61530 ) Arabidopsis thaliana CML076C Cyanidioschyzon merolae strain 10D 196344 Chlamydomonas reinhardtii ACO65489 Micromonas sp. RCC299 NP_001042460 Oryza sativa Japonica Group estExt_gwp_GeneWisePlus.C_Chr_02.00010475 Ostreococcus tauri estExt_fgenesh2_pg.C_1300083 Physcomitrella patens subsp. patens 30174.m008666 Ricinus communis 39910.m000014 Ricinus communis fgenesh1_pg.C_chr_3000893 Thalassiosira pseudonana CCMP1335 XP_002948147 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR20881 2.8E-164 17 349 IPR003700 Ketopantoate hydroxymethyltransferase Pfam PF02548 1.9E-104 43 307 IPR003700 Ketopantoate hydroxymethyltransferase SUPERFAMILY SSF51621 8.2E-96 43 309 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain Hamap MF_00156 40.0 44 311 IPR003700 Ketopantoate hydroxymethyltransferase TIGRFAM TIGR00222 2.3E-88 45 310 IPR003700 Ketopantoate hydroxymethyltransferase
Subcellular Localization
Localization	mitochondrion
Evidence	SUBAcon
Pubmed ID	23180787