Basic information
Locus name	AT3G12120
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Lipid/Carbohydrate metabolism:Lipid metabolism
Effect for Senescence	Unclear
Gene Description	Omega-6 fatty acid desaturase. Upregulated in senescent leaves.
Evidence	Molecular evidence: SSH and Northern [Ref 1]
References	1: Gepstein S, Sabehi G, Carp MJ, Hajouj T, Nesher MF, Yariv I, Dor C, Bassani M Large-scale identification of leaf senescence-associated genes. Plant J. 2003 Dec;36(5):629-42
Gene Ontology	biological process lipid metabolic process oxidation-reduction process molecular function oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
Pathway	KEGG map00592 (EC 1.14.19.-)
Sequence	AT3G12120.1 | Genomic | mRNA | CDS | Protein AT3G12120.2 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT3G12120.1  miRNA: ath-miR157a miRNA: ath-miR157a mfe: -24.8 kcal/mol  p-value: 0.010818  position:  1361  target 5' U  U  G               A 3'             UG CU UUUGUCUUUUGUUAA              AC GA AGAUAGAAGACAGUU   miRNA  3' C     G                 5'  target: AT3G12120.1  miRNA: ath-miR157b miRNA: ath-miR157b mfe: -24.8 kcal/mol  p-value: 0.010635  position:  1361  target 5' U  U  G               A 3'             UG CU UUUGUCUUUUGUUAA              AC GA AGAUAGAAGACAGUU   miRNA  3' C     G                 5'  target: AT3G12120.1  miRNA: ath-miR157c miRNA: ath-miR157c mfe: -24.8 kcal/mol  p-value: 0.010268  position:  1361  target 5' U  U  G               A 3'             UG CU UUUGUCUUUUGUUAA              AC GA AGAUAGAAGACAGUU   miRNA  3' C     G                 5'  target: AT3G12120.1  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -21.6 kcal/mol  p-value: 0.108701  position:  1271  target 5' A   C         A  G   C 3'             GAA CGGACAGGG AG UGA              CUU GCUUGUUCU UU ACU   miRNA  3' A   U            G   A 5'  target: AT3G12120.2  miRNA: ath-miR157a miRNA: ath-miR157a mfe: -24.8 kcal/mol  p-value: 0.009459  position:  1322  target 5' U  U  G               A 3'             UG CU UUUGUCUUUUGUUAA              AC GA AGAUAGAAGACAGUU   miRNA  3' C     G                 5'  target: AT3G12120.2  miRNA: ath-miR157b miRNA: ath-miR157b mfe: -24.8 kcal/mol  p-value: 0.009219  position:  1322  target 5' U  U  G               A 3'             UG CU UUUGUCUUUUGUUAA              AC GA AGAUAGAAGACAGUU   miRNA  3' C     G                 5'  target: AT3G12120.2  miRNA: ath-miR157c miRNA: ath-miR157c mfe: -24.8 kcal/mol  p-value: 0.008603  position:  1322  target 5' U  U  G               A 3'             UG CU UUUGUCUUUUGUUAA              AC GA AGAUAGAAGACAGUU   miRNA  3' C     G                 5'  target: AT3G12120.2  miRNA: ath-miR837-5p miRNA: ath-miR837-5p mfe: -21.6 kcal/mol  p-value: 0.096045  position:  1232  target 5' A   C         A  G   C 3'             GAA CGGACAGGG AG UGA              CUU GCUUGUUCU UU ACU   miRNA  3' A   U            G   A 5'
Ortholog Group
Ortholog Groups: OG5_129048	Accession Taxon NP_001078140 ( AT3G12120 ) Arabidopsis thaliana NP_187819 Arabidopsis thaliana CMK291C Cyanidioschyzon merolae strain 10D 135825 Chlamydomonas reinhardtii ACO63575 Micromonas sp. RCC299 ACO68349 Micromonas sp. RCC299 NP_001047927 Oryza sativa Japonica Group NP_001059466 Oryza sativa Japonica Group NP_001059467 Oryza sativa Japonica Group estExt_genewise1.C_Chr_17.00010051 Ostreococcus tauri fgenesh1_pm.C_Chr_02.0001000095 Ostreococcus tauri estExt_gwp_gw1.C_210129 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_300081 Physcomitrella patens subsp. patens 28035.m000362 Ricinus communis 29613.m000358 Ricinus communis 29681.m001360 Ricinus communis estExt_fgenesh1_pg.C_chr_80319 Thalassiosira pseudonana CCMP1335 estExt_gwp_gw1.C_chr_60251 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_3000077 Thalassiosira pseudonana CCMP1335 XP_002955859 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR32100 0.0 1 383 No hit NA Pfam PF11960 6.4E-7 16 63 IPR021863 Protein of unknown function DUF3474 Pfam PF00487 2.7E-33 83 344 IPR005804 Fatty acid desaturase, type 1
Subcellular Localization
Localization	endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787