Basic information
Locus name	AT4G18780
Alias	IRX1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	IRREGULAR XYLEM 1 (IRX1); FUNCTIONS IN: cellulose synthase activity, transferase activity, transferring glycosyl groups; INVOLVED IN: in 10 processes; LOCATED IN: cell wall, plasma membrane; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Cellulose synthase (InterPro:IPR005150), Zinc finger, RING-type, conserved site (InterPro:IPR017907), Zinc finger, RING-type (InterPro:IPR001841), Zinc finger, RING/FYVE/PHD-type (InterPro:IPR013083); BEST Arabidopsis thaliana protein match is: CESA4 (CELLULOSE SYNTHASE A4); cellulose synthase/ transferase, transferring glycosyl groups (TAIR:AT5G44030.1); Has 2171 Blast hits to 1913 proteins in 422 species: Archae - 4; Bacteria - 706; Metazoa - 3; Fungi - 20; Plants - 1374; Viruses - 3; Other Eukaryotes - 61 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process cellulose biosynthetic process cellular component membrane molecular function cellulose synthase (UDP-forming) activity
Sequence	AT4G18780.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_129836	Accession Taxon NP_171773 Arabidopsis thaliana NP_174497 Arabidopsis thaliana NP_179768 Arabidopsis thaliana NP_180124 Arabidopsis thaliana NP_180869 Arabidopsis thaliana NP_186955 Arabidopsis thaliana NP_194967 Arabidopsis thaliana NP_195532 Arabidopsis thaliana NP_195645 Arabidopsis thaliana NP_196136 Arabidopsis thaliana NP_196549 Arabidopsis thaliana NP_197193 Arabidopsis thaliana NP_197244 Arabidopsis thaliana NP_199216 Arabidopsis thaliana NP_201279 Arabidopsis thaliana NP_567564 ( AT4G18780 ) Arabidopsis thaliana NP_001044252 Oryza sativa Japonica Group NP_001051648 Oryza sativa Japonica Group NP_001051830 Oryza sativa Japonica Group NP_001054788 Oryza sativa Japonica Group NP_001056589 Oryza sativa Japonica Group NP_001057557 Oryza sativa Japonica Group NP_001059162 Oryza sativa Japonica Group NP_001059303 Oryza sativa Japonica Group NP_001059487 Oryza sativa Japonica Group NP_001059944 Oryza sativa Japonica Group NP_001059945 Oryza sativa Japonica Group NP_001059946 Oryza sativa Japonica Group NP_001059947 Oryza sativa Japonica Group NP_001059948 Oryza sativa Japonica Group NP_001061048 Oryza sativa Japonica Group NP_001063207 Oryza sativa Japonica Group NP_001064390 Oryza sativa Japonica Group NP_001064811 Oryza sativa Japonica Group e_gw1.243.47.1 Physcomitrella patens subsp. patens e_gw1.29.2.1 Physcomitrella patens subsp. patens e_gw1.310.1.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_80120 Physcomitrella patens subsp. patens estExt_Genewise1.C_900171 Physcomitrella patens subsp. patens estExt_fgenesh1_pg.C_2130003 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_2690004 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_300004 Physcomitrella patens subsp. patens estExt_fgenesh2_pg.C_1110020 Physcomitrella patens subsp. patens estExt_fgenesh2_pg.C_1110026 Physcomitrella patens subsp. patens estExt_fgenesh2_pg.C_1120025 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1890065 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1890069 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2430005 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_570039 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_680137 Physcomitrella patens subsp. patens 28093.m000117 Ricinus communis 29482.m000171 Ricinus communis 29606.m000101 Ricinus communis 29637.m000754 Ricinus communis 29761.m000416 Ricinus communis 29848.m004649 Ricinus communis 29863.m001055 Ricinus communis 29904.m002970 Ricinus communis 29986.m001674 Ricinus communis 30026.m001452 Ricinus communis 30068.m002658 Ricinus communis 30073.m002256 Ricinus communis 30162.m001289 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR13301 0.0 1 985 No hit NA SUPERFAMILY SSF57850 3.2E-24 2 60 No hit NA Pfam PF03552 0.0 263 977 IPR005150 Cellulose synthase SUPERFAMILY SSF53448 2.1E-9 277 327 No hit NA SUPERFAMILY SSF53448 2.1E-9 431 552 No hit NA SUPERFAMILY SSF53448 2.1E-9 661 763 No hit NA
Subcellular Localization
Localization	extracellular,plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787