Basic information
Locus name	AT1G62300
Alias	WRKY6
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:WRKY
Effect for Senescence	promote
Gene Description	Encodes a transcription factor WRKY6. Regulates Phosphate1 (Pho1) expression in response to low phosphate (Pi) stress. WRKY6 plays a role in regulating by controling SIRK gene expression.
Evidence	Genetic evidence: mutant [Ref 1, Ref 2]; Molecular evidence:Northern [Ref 3]; Genomic evidence:microarray data [Ref 4]
References	1: Robatzek S, Somssich IE A new member of the Arabidopsis WRKY transcription factor family, AtWRKY6, is associated with both senescence- and defence-related processes. Plant J. 2001 Oct;28(2):123-33 2: Robatzek S, Somssich IE Targets of AtWRKY6 regulation during plant senescence and pathogen defense. Genes Dev. 2002 May 1;16(9):1139-49 3: Kim CY, Bove J, Assmann SM Overexpression of wound-responsive RNA-binding proteins induces leaf senescence and hypersensitive-like cell death. New Phytol. 2008;180(1):57-70 4: Libault M, Wan J, Czechowski T, Udvardi M, Stacey G Identification of 118 Arabidopsis transcription factor and 30 ubiquitin-ligase genes responding to chitin, a plant-defense elicitor. Mol. Plant Microbe Interact. 2007 Aug;20(8):900-11 5: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function sequence-specific DNA binding transcription factor activity sequence-specific DNA binding
Sequence	AT1G62300.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutant name	wrky6
Mutant/Transgenic	mutant
Ecotype	Col-0
Mutagenesis type	T-DNA insertion_knock out
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_164568	Accession Taxon NP_192354 Arabidopsis thaliana NP_564792 ( AT1G62300 ) Arabidopsis thaliana NP_567644 Arabidopsis thaliana NP_001042577 Oryza sativa Japonica Group 29842.m003555 Ricinus communis 30010.m000675 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31429 7.1E-172 1 552 No hit NA Coils Coil NA 150 178 No hit NA SUPERFAMILY SSF118290 4.6E-28 304 372 IPR003657 DNA-binding WRKY ProSiteProfiles PS50811 29.8 306 372 IPR003657 DNA-binding WRKY SMART SM00774 2.4E-37 311 371 IPR003657 DNA-binding WRKY Pfam PF03106 2.4E-28 312 370 IPR003657 DNA-binding WRKY
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787