Basic information
Locus name	AT3G57550
Alias	AGK2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	GUANYLATE KINASE (AGK2); FUNCTIONS IN: guanylate kinase activity; INVOLVED IN: nucleotide metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Guanylate kinase (InterPro:IPR008144), Guanylate kinase/L-type calcium channel region (InterPro:IPR008145), Guanylate kinase, sub-group (InterPro:IPR017665); BEST Arabidopsis thaliana protein match is: GK-1 (GUANYLATE KINASE 1); guanylate kinase (TAIR:AT2G41880.1); Has 6781 Blast hits to 6765 proteins in 1550 species: Archae - 0; Bacteria - 2905; Metazoa - 1214; Fungi - 106; Plants - 89; Viruses - 104; Other Eukaryotes - 2363 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	molecular function guanylate kinase activity protein binding
Pathway	KEGG map00230 (EC 2.7.4.8) MetaCyc PWY-6125
Sequence	AT3G57550.1 | Genomic | mRNA | CDS | Protein AT3G57550.2 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT3G57550.1  miRNA: ath-miR838 miRNA: ath-miR838 mfe: -28.3 kcal/mol  p-value: 0.003261  position: 1314  target 5' G                   U  3'             GUGU AGAAGUAGAAGGGA                 CACG UCUUCAUCUUCUUU      miRNA  3' A    U              U  5'
Ortholog Group
Ortholog Groups: OG5_126916	Accession Taxon NP_001030877 ( AT3G57550 ) Arabidopsis thaliana NP_565961 Arabidopsis thaliana NP_566276 Arabidopsis thaliana NP_567051 Arabidopsis thaliana CMD076C Cyanidioschyzon merolae strain 10D CMI041C Cyanidioschyzon merolae strain 10D CMS484C Cyanidioschyzon merolae strain 10D 103296 Chlamydomonas reinhardtii 111725 Chlamydomonas reinhardtii 174270 Chlamydomonas reinhardtii ACO60832 Micromonas sp. RCC299 ACO66128 Micromonas sp. RCC299 NP_001049956 Oryza sativa Japonica Group NP_001066887 Oryza sativa Japonica Group estExt_fgenesh1_pm.C_Chr_12.00010039 Ostreococcus tauri e_gw1.145.149.1 Physcomitrella patens subsp. patens e_gw1.2.257.1 Physcomitrella patens subsp. patens e_gw1.284.41.1 Physcomitrella patens subsp. patens e_gw1.46.153.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_2040023 Physcomitrella patens subsp. patens 29726.m003918 Ricinus communis 29761.m000433 Ricinus communis e_gw1.16a.58.1 Thalassiosira pseudonana CCMP1335 fgenesh1_pg.C_chr_3000382 Thalassiosira pseudonana CCMP1335 XP_002947596 Volvox carteri f. nagariensis XP_002953018 Volvox carteri f. nagariensis XP_002959912 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23117 4.6E-212 12 333 No hit NA SUPERFAMILY SSF50965 1.7E-8 22 117 IPR011043 Galactose oxidase/kelch, beta-propeller SMART SM00072 5.3E-86 136 322 IPR008145 Guanylate kinase/L-type calcium channel Pfam PF00625 6.3E-59 137 318 IPR008144 Guanylate kinase ProSiteProfiles PS50052 42.4 137 319 IPR008144 Guanylate kinase SUPERFAMILY SSF52540 7.0E-64 138 318 IPR027417 P-loop containing nucleoside triphosphate hydrolase TIGRFAM TIGR03263 5.9E-63 138 317 IPR017665 Guanylate kinase, sub-group ProSitePatterns PS00856 NA 172 189 IPR020590 Guanylate kinase, conserved site