Basic information
Locus name	AT5G40370
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	glutaredoxin, putative; FUNCTIONS IN: electron carrier activity, arsenate reductase (glutaredoxin) activity, protein disulfide oxidoreductase activity; INVOLVED IN: cell redox homeostasis; LOCATED IN: plasma membrane, vacuole; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Glutaredoxin (InterPro:IPR002109), Thioredoxin fold (InterPro:IPR012335), Glutaredoxin subgroup (InterPro:IPR014025), Glutaredoxin active site (InterPro:IPR011767), Glutaredoxin, eukaryotic and viruses (InterPro:IPR011899), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: glutaredoxin, putative (TAIR:AT5G63030.1); Has 6100 Blast hits to 6075 proteins in 885 species: Archae - 0; Bacteria - 2513; Metazoa - 527; Fungi - 301; Plants - 521; Viruses - 107; Other Eukaryotes - 2131 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process cell redox homeostasis molecular function electron carrier activity protein disulfide oxidoreductase activity
Sequence	AT5G40370.1 | Genomic | mRNA | CDS | Protein AT5G40370.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126864	Accession Taxon NP_001119339 ( AT5G40370 ) Arabidopsis thaliana NP_177861 Arabidopsis thaliana NP_197550 Arabidopsis thaliana NP_198853 Arabidopsis thaliana NP_568962 Arabidopsis thaliana CMF017C Cyanidioschyzon merolae strain 10D CMT629C Cyanidioschyzon merolae strain 10D 195611 Chlamydomonas reinhardtii 195746 Chlamydomonas reinhardtii ACO65484 Micromonas sp. RCC299 ACO65493 Micromonas sp. RCC299 ACO69112 Micromonas sp. RCC299 NP_001047447 Oryza sativa Japonica Group NP_001047574 Oryza sativa Japonica Group NP_001053270 Oryza sativa Japonica Group e_gw1.321.8.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1850003 Physcomitrella patens subsp. patens gw1.131.144.1 Physcomitrella patens subsp. patens 29279.m000134 Ricinus communis 29662.m000463 Ricinus communis 29933.m001414 Ricinus communis 30147.m013927 Ricinus communis 44776.m000022 Ricinus communis estExt_Genewise1.C_chr_20178 Thalassiosira pseudonana CCMP1335 gw1.1.862.1 Thalassiosira pseudonana CCMP1335 thaps1_ua_kg.chr_2000102 Thalassiosira pseudonana CCMP1335 XP_002947896 Volvox carteri f. nagariensis XP_002956386 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description ProSiteProfiles PS51354 22.2 28 128 IPR002109 Glutaredoxin PRINTS PR00160 5.2E-16 40 58 IPR014025 Glutaredoxin subgroup PANTHER PTHR10168 4.4E-38 42 128 No hit NA TIGRFAM TIGR02180 3.9E-28 42 120 IPR011899 Glutaredoxin, eukaryotic/virial Pfam PF00462 5.4E-20 43 102 IPR002109 Glutaredoxin SUPERFAMILY SSF52833 8.1E-28 44 127 IPR012336 Thioredoxin-like fold PRINTS PR00160 5.2E-16 85 98 IPR014025 Glutaredoxin subgroup PRINTS PR00160 5.2E-16 99 112 IPR014025 Glutaredoxin subgroup
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787