Basic information
Locus name	AT3G28850
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	glutaredoxin family protein; FUNCTIONS IN: electron carrier activity, protein disulfide oxidoreductase activity; INVOLVED IN: N-terminal protein myristoylation, cell redox homeostasis; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Glutaredoxin (InterPro:IPR002109), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: glutaredoxin family protein (TAIR:AT5G39865.1); Has 422 Blast hits to 412 proteins in 81 species: Archae - 0; Bacteria - 39; Metazoa - 112; Fungi - 14; Plants - 211; Viruses - 0; Other Eukaryotes - 46 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process cell redox homeostasis molecular function electron carrier activity protein disulfide oxidoreductase activity
Sequence	AT3G28850.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT3G28850.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -37.8 kcal/mol  p-value: 0.000041  position: 1165  target 5' A                     U  3'             UGAUGAUGAUGAUGAAGGUGA                 ACUGCUACUACUACUUCUACU      miRNA  3'                          5'  target: AT3G28850.1  miRNA: ath-miR838 miRNA: ath-miR838 mfe: -29.2 kcal/mol  p-value: 0.001653  position: 1036  target 5' G        G            C  3'             GUGUGAGA GGUGGAAGAAAA                 CACGUUCU UCAUCUUCUUUU      miRNA  3' A                        5'
Ortholog Group
Ortholog Groups: OG5_164535	Accession Taxon NP_189527 ( AT3G28850 ) Arabidopsis thaliana NP_680368 Arabidopsis thaliana NP_001048121 Oryza sativa Japonica Group NP_001054043 Oryza sativa Japonica Group NP_001057202 Oryza sativa Japonica Group 29822.m003499 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description Coils Coil NA 94 115 No hit NA PANTHER PTHR10168 1.5E-90 187 427 No hit NA ProSiteProfiles PS51354 17.3 241 351 IPR002109 Glutaredoxin SUPERFAMILY SSF52833 6.4E-20 246 345 IPR012336 Thioredoxin-like fold Pfam PF00462 8.5E-10 254 325 IPR002109 Glutaredoxin
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787