Basic information
Locus name	AT5G58870
Alias	FTSH9
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Protein degradation/modification
Effect for Senescence	unclear
Gene Description	FtsH protease 9 (ftsh9); FUNCTIONS IN: metallopeptidase activity, ATP-dependent peptidase activity, ATPase activity; INVOLVED IN: proteolysis, protein catabolic process; LOCATED IN: chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M41, FtsH (InterPro:IPR005936), ATPase, AAA+ type, core (InterPro:IPR003593), ATPase, AAA-type, core (InterPro:IPR003959), ATPase, AAA-type, conserved site (InterPro:IPR003960), Peptidase M41 (InterPro:IPR000642), Peptidase M41, FtsH extracellular (InterPro:IPR011546); BEST Arabidopsis thaliana protein match is: ftsh7 (FtsH protease 7); ATP-dependent peptidase/ ATPase/ metallopeptidase (TAIR:AT3G47060.1); Has 29029 Blast hits to 27283 proteins in 1906 species: Archae - 899; Bacteria - 9718; Metazoa - 4183; Fungi - 2378; Plants - 1791; Viruses - 24; Other Eukaryotes - 10036 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process protein catabolic process proteolysis cellular component membrane molecular function ATP binding metalloendopeptidase activity zinc ion binding
Sequence	AT5G58870.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT5G58870.1  miRNA: ath-miR397b miRNA: ath-miR397b mfe: -31.9 kcal/mol  p-value: 0.001659  position: 2067  target 5' A       A              U  3'             UAUCAAC GGUGCACUUGAUGA                 GUAGUUG CUACGUGAGUUACU      miRNA  3'                           5'
Ortholog Group
Ortholog Groups: OG5_156642	Accession Taxon NP_566889 Arabidopsis thaliana NP_568892 ( AT5G58870 ) Arabidopsis thaliana 97032 Chlamydomonas reinhardtii ACO64810 Micromonas sp. RCC299 NP_001047584 Oryza sativa Japonica Group gw1.10.00.39.1 Ostreococcus tauri e_gw1.10.22.1 Physcomitrella patens subsp. patens 29681.m001304 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23076 0.0 4 791 No hit NA Hamap MF_01458 30.9 33 786 IPR005936 Peptidase, FtsH Pfam PF06480 1.5E-9 140 266 IPR011546 Peptidase M41, FtsH extracellular TIGRFAM TIGR01241 1.0E-163 293 776 IPR005936 Peptidase, FtsH SUPERFAMILY SSF52540 2.6E-66 326 571 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMART SM00382 2.5E-23 361 501 IPR003593 AAA+ ATPase domain Pfam PF00004 2.5E-43 365 498 IPR003959 ATPase, AAA-type, core ProSitePatterns PS00674 NA 469 487 IPR003960 ATPase, AAA-type, conserved site Pfam PF01434 3.8E-42 564 776 IPR000642 Peptidase M41 SUPERFAMILY SSF140990 7.6E-42 584 779 No hit NA
Subcellular Localization
Localization 1 Localization chloroplast Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization plastid Evidence SUBAcon Pubmed ID 23180787