Basic information
Locus name	AT5G23440
Alias	FTRA1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	ferredoxin/thioredoxin reductase subunit A (variable subunit) 1 (FTRA1); FUNCTIONS IN: ferredoxin:thioredoxin reductase activity, lipoate synthase activity, catalytic activity, ferredoxin reductase activity; INVOLVED IN: photosynthesis, light reaction, lipoate biosynthetic process, photosynthesis; LOCATED IN: chloroplast; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Lipoate synthase (InterPro:IPR003698), Ferredoxin thioredoxin reductase, alpha chain (InterPro:IPR004207), Electron transport accessory protein (InterPro:IPR008990); BEST Arabidopsis thaliana protein match is: FTRA2 (ferredoxin/thioredoxin reductase subunit A (variable subunit) 2); catalytic/ ferredoxin reductase/ ferredoxin:thioredoxin reductase/ lipoate synthase (TAIR:AT5G08410.1); Has 111 Blast hits to 111 proteins in 43 species: Archae - 0; Bacteria - 63; Metazoa - 0; Fungi - 1; Plants - 46; Viruses - 0; Other Eukaryotes - 1 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process lipoate biosynthetic process photosynthesis molecular function 4 iron, 4 sulfur cluster binding lipoate synthase activity
Pathway	KEGG map00785 (EC 2.8.1.8)
Sequence	AT5G23440.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_139567	Accession Taxon NP_197735 ( AT5G23440 ) Arabidopsis thaliana NP_568195 Arabidopsis thaliana CMP058C Cyanidioschyzon merolae strain 10D 151962 Chlamydomonas reinhardtii 185233 Chlamydomonas reinhardtii ACO61954 Micromonas sp. RCC299 NP_001047533 Oryza sativa Japonica Group NP_001053378 Oryza sativa Japonica Group fgenesh1_pg.C_Chr_02.0001000208 Ostreococcus tauri e_gw1.102.95.1 Physcomitrella patens subsp. patens e_gw1.6.265.1 Physcomitrella patens subsp. patens e_gw1.6.266.1 Physcomitrella patens subsp. patens gw1.102.94.1 Physcomitrella patens subsp. patens 30131.m007297 Ricinus communis XP_002958221 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10949 6.9E-85 52 182 IPR003698 Lipoyl synthase SUPERFAMILY SSF50090 1.4E-23 103 180 IPR008990 Electron transport accessory protein-like domain Pfam PF02941 7.5E-29 104 176 IPR004207 Ferredoxin thioredoxin reductase, alpha chain
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787