Basic information
Locus name	AT5G39610
Alias	ORE1/AtNAC092/AtNAC2/AtNAC06
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Transcription regulation:NAC
Effect for Senescence	promote
Gene Description	ORE1 expression is up-regulated concurrently with leaf aging by EIN2 but is negatively regulated by miR164. miR164 expression gradually decreases with aging through negative regulation by EIN2, which leads to the elaborate up-regulation of ORE1 expression.
Evidence	Genetic evidence:Mutant [Ref 1, Ref 2]; Genomic evidence:microarray data [Ref 3]
References	1: Kim JH, Woo HR, Kim J, Lim PO, Lee IC, Choi SH, Hwang D, Nam HG Trifurcate feed-forward regulation of age-dependent cell death involving miR164 in Arabidopsis. Science 2009 Feb 20;323(5917):1053-7 2: Balazadeh S, Siddiqui H, Allu AD, Matallana-Ramirez LP, Caldana C, Mehrnia M, Zanor MI, K_hler B, Mueller-Roeber B A gene regulatory network controlled by the NAC transcription factor ANAC092/AtNAC2/ORE1 during salt-promoted senescence. Plant J. 2010 Apr;62(2):250-64 3: Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4):567-85
Gene Ontology	biological process regulation of transcription, DNA-dependent molecular function DNA binding
Sequence	AT5G39610.1 | Genomic | mRNA | CDS | Protein
Mutant information
Mutated 1 Mutant name ore1-1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type EMS
Mutated 2 Mutant name ors1-1/anac092-1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 3 Mutant name anac092-1 Mutant/Transgenic mutant Ecotype Col-0 Mutagenesis type T-DNA insertion_knock out
Mutated 4 Mutant name ANAC092-IOE Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Mutated 5 Mutant name 35S:ANAC092 Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Mutated 6 Mutant name ANAC092-RNAi Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type RNAi
Mutated 7 Mutant name 35S:ORE1 Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Mutated 8 Mutant name 35S:ORE1/35S:GLK2 Mutant/Transgenic transgenic Ecotype Col-0 Mutagenesis type transgene
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_212463	Accession Taxon NP_189546 Arabidopsis thaliana NP_198777 ( AT5G39610 ) Arabidopsis thaliana
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR31744 5.0E-156 1 273 No hit NA SUPERFAMILY SSF101941 5.9E-64 16 170 IPR003441 No apical meristem (NAM) protein Pfam PF02365 3.1E-54 20 146 IPR003441 No apical meristem (NAM) protein ProSiteProfiles PS51005 59.7 20 170 IPR003441 No apical meristem (NAM) protein
Subcellular Localization
Localization	nucleus
Evidence	SUBAcon
Pubmed ID	23180787