Basic information
Locus name	AT4G11170
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	disease resistance protein (TIR-NBS-LRR class), putative; FUNCTIONS IN: protein binding, transmembrane receptor activity, nucleoside-triphosphatase activity, nucleotide binding, ATP binding; INVOLVED IN: response to ozone, defense response; LOCATED IN: mitochondrion; EXPRESSED IN: stem, root, stamen; EXPRESSED DURING: 4 anthesis; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), NB-ARC (InterPro:IPR002182), Leucine-rich repeat (InterPro:IPR001611), Toll-Interleukin receptor (InterPro:IPR000157), Leucine-rich repeat 3 (InterPro:IPR011713); BEST Arabidopsis thaliana protein match is: disease resistance protein (TIR-NBS-LRR class), putative (TAIR:AT5G49140.1); Has 12533 Blast hits to 9945 proteins in 399 species: Archae - 16; Bacteria - 576; Metazoa - 873; Fungi - 40; Plants - 10831; Viruses - 0; Other Eukaryotes - 197 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process defense response signal transduction molecular function ADP binding protein binding
Sequence	AT4G11170.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_129307	Accession Taxon NP_001077768 Arabidopsis thaliana NP_001077769 Arabidopsis thaliana NP_001078237 Arabidopsis thaliana NP_001117396 Arabidopsis thaliana NP_001118772 Arabidopsis thaliana NP_001154443 Arabidopsis thaliana NP_001154444 Arabidopsis thaliana NP_001154757 Arabidopsis thaliana NP_174439 Arabidopsis thaliana NP_176043 Arabidopsis thaliana NP_176044 Arabidopsis thaliana NP_176047 Arabidopsis thaliana NP_176560 Arabidopsis thaliana NP_176561 Arabidopsis thaliana NP_176562 Arabidopsis thaliana NP_176571 Arabidopsis thaliana NP_176572 Arabidopsis thaliana NP_176590 Arabidopsis thaliana NP_176760 Arabidopsis thaliana NP_179024 Arabidopsis thaliana NP_179279 Arabidopsis thaliana NP_187072 Arabidopsis thaliana NP_189178 Arabidopsis thaliana NP_190026 Arabidopsis thaliana NP_190034 Arabidopsis thaliana NP_190049 Arabidopsis thaliana NP_190053 Arabidopsis thaliana NP_192585 Arabidopsis thaliana NP_192855 ( AT4G11170 ) Arabidopsis thaliana NP_193173 Arabidopsis thaliana NP_193420 Arabidopsis thaliana NP_193422 Arabidopsis thaliana NP_193424 Arabidopsis thaliana NP_193425 Arabidopsis thaliana NP_193427 Arabidopsis thaliana NP_193428 Arabidopsis thaliana NP_193429 Arabidopsis thaliana NP_196686 Arabidopsis thaliana NP_197298 Arabidopsis thaliana NP_197336 Arabidopsis thaliana NP_197337 Arabidopsis thaliana NP_197338 Arabidopsis thaliana NP_197661 Arabidopsis thaliana NP_198650 Arabidopsis thaliana NP_198651 Arabidopsis thaliana NP_198701 Arabidopsis thaliana NP_198822 Arabidopsis thaliana NP_198907 Arabidopsis thaliana NP_198969 Arabidopsis thaliana NP_198970 Arabidopsis thaliana NP_198989 Arabidopsis thaliana NP_198990 Arabidopsis thaliana NP_199264 Arabidopsis thaliana NP_199438 Arabidopsis thaliana NP_199439 Arabidopsis thaliana NP_199457 Arabidopsis thaliana NP_199459 Arabidopsis thaliana NP_199463 Arabidopsis thaliana NP_199464 Arabidopsis thaliana NP_199725 Arabidopsis thaliana NP_199976 Arabidopsis thaliana NP_200620 Arabidopsis thaliana NP_564971 Arabidopsis thaliana NP_566223 Arabidopsis thaliana NP_568664 Arabidopsis thaliana NP_849398 Arabidopsis thaliana NP_850654 Arabidopsis thaliana NP_850655 Arabidopsis thaliana NP_851117 Arabidopsis thaliana NP_851172 Arabidopsis thaliana NP_974894 Arabidopsis thaliana
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11017 0.0 1 908 No hit NA SUPERFAMILY SSF52200 5.1E-40 3 149 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain ProSiteProfiles PS50104 27.2 9 147 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain SMART SM00255 2.0E-58 10 147 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain Pfam PF01582 5.4E-41 13 142 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain SUPERFAMILY SSF52540 1.4E-57 173 437 IPR027417 P-loop containing nucleoside triphosphate hydrolase Pfam PF00931 2.7E-35 188 452 IPR002182 NB-ARC SMART SM00382 2.0E-6 204 388 IPR003593 AAA+ ATPase domain PRINTS PR00364 6.7E-22 207 222 IPR000767 Disease resistance protein PRINTS PR00364 6.7E-22 285 299 IPR000767 Disease resistance protein PRINTS PR00364 6.7E-22 378 392 IPR000767 Disease resistance protein SUPERFAMILY SSF46785 3.1E-10 414 500 No hit NA SUPERFAMILY SSF52058 2.3E-33 544 845 No hit NA Pfam PF07725 4.6E-7 609 628 IPR011713 Leucine-rich repeat 3 PRINTS PR00364 6.7E-22 628 644 IPR000767 Disease resistance protein
Subcellular Localization
Localization 1 Localization mitochondria Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization mitochondrion Evidence SUBAcon Pubmed ID 23180787