Basic information
Locus name	AT5G13570
Alias	DCP2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	DECAPPING 2 (DCP2); FUNCTIONS IN: hydrolase activity, mRNA binding, m7G(5')pppN diphosphatase activity, protein homodimerization activity; INVOLVED IN: mRNA catabolic process, deadenylation-independent decapping of nuclear-transcribed mRNA; LOCATED IN: cytoplasmic mRNA processing body, cytoplasm; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: NUDIX (InterPro:IPR015797), Dcp2, box A (InterPro:IPR007722), NUDIX hydrolase, core (InterPro:IPR000086); Has 607 Blast hits to 603 proteins in 197 species: Archae - 11; Bacteria - 144; Metazoa - 123; Fungi - 108; Plants - 26; Viruses - 8; Other Eukaryotes - 187 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	molecular function RNA binding hydrolase activity manganese ion binding
Sequence	AT5G13570.1 | Genomic | mRNA | CDS | Protein AT5G13570.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_128366	Accession Taxon NP_196861 ( AT5G13570 ) Arabidopsis thaliana CMJ226C Cyanidioschyzon merolae strain 10D 146010 Chlamydomonas reinhardtii ACO69326 Micromonas sp. RCC299 NP_001048445 Oryza sativa Japonica Group estExt_fgenesh1_pg.C_Chr_08.00010184 Ostreococcus tauri e_gw1.358.37.1 Physcomitrella patens subsp. patens e_gw1.51.237.1 Physcomitrella patens subsp. patens e_gw1.59.280.1 Physcomitrella patens subsp. patens 27516.m000173 Ricinus communis estExt_fgenesh1_pg.C_chr_40448 Thalassiosira pseudonana CCMP1335 XP_002950367 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR23114 4.1E-299 1 373 No hit NA SUPERFAMILY SSF140586 7.5E-33 16 105 No hit NA Pfam PF05026 1.8E-27 22 105 IPR007722 mRNA decapping protein 2, Box A ProSiteProfiles PS51462 13.2 106 234 IPR000086 NUDIX hydrolase domain SUPERFAMILY SSF55811 2.3E-22 108 234 IPR015797 NUDIX hydrolase domain-like Pfam PF00293 5.1E-14 111 218 IPR000086 NUDIX hydrolase domain ProSitePatterns PS00893 NA 139 160 IPR020084 NUDIX hydrolase, conserved site