Basic information
Locus name	AT4G05420
Alias	DDB1A
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	DAMAGED DNA BINDING PROTEIN 1A (DDB1A); FUNCTIONS IN: protein binding, DNA binding; INVOLVED IN: negative regulation of transcription, negative regulation of photomorphogenesis; LOCATED IN: nucleus, CUL4 RING ubiquitin ligase complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: WD40 repeat-like (InterPro:IPR011046), Cleavage and polyadenylation specificity factor, A subunit, C-terminal (InterPro:IPR004871); BEST Arabidopsis thaliana protein match is: DDB1B (Damaged DNA Binding Protein 1 B); damaged DNA binding / protein binding (TAIR:AT4G21100.1); Has 1108 Blast hits to 865 proteins in 168 species: Archae - 0; Bacteria - 0; Metazoa - 516; Fungi - 248; Plants - 129; Viruses - 0; Other Eukaryotes - 215 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	cellular component nucleus molecular function nucleic acid binding protein binding
Sequence	AT4G05420.1 | Genomic | mRNA | CDS | Protein AT4G05420.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_129644	Accession Taxon NP_001118940 Arabidopsis thaliana NP_192451 ( AT4G05420 ) Arabidopsis thaliana NP_193842 Arabidopsis thaliana CMR264C Cyanidioschyzon merolae strain 10D 133572 Chlamydomonas reinhardtii ACO65083 Micromonas sp. RCC299 NP_001056495 Oryza sativa Japonica Group gw1.10.00.14.1 Ostreococcus tauri estExt_Genewise1.C_2030018 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_458000001 Physcomitrella patens subsp. patens 29932.m000602 Ricinus communis fgenesh1_pg.C_chr_2000137 Thalassiosira pseudonana CCMP1335 XP_002950181 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10644 0.0 3 1088 No hit NA Pfam PF10433 6.5E-100 76 540 No hit NA Coils Coil NA 422 443 No hit NA SUPERFAMILY SSF50978 3.4E-8 457 683 IPR017986 WD40-repeat-containing domain Pfam PF03178 2.7E-83 744 1057 IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminal SUPERFAMILY SSF50978 3.4E-8 801 838 IPR017986 WD40-repeat-containing domain
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization nucleus Evidence SUBAcon Pubmed ID 23180787