Basic information
Locus name	AT4G37310
Alias	CYP81H1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Redox regulation
Effect for Senescence	unclear
Gene Description	CYP81H1; FUNCTIONS IN: electron carrier activity, monooxygenase activity, iron ion binding, oxygen binding, heme binding; LOCATED IN: endomembrane system; EXPRESSED IN: 18 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Cytochrome P450 (InterPro:IPR001128), Cytochrome P450, C-terminal region (InterPro:IPR017973), Cytochrome P450, E-class, group I (InterPro:IPR002401), Cytochrome P450, conserved site (InterPro:IPR017972); BEST Arabidopsis thaliana protein match is: CYP81D8; electron carrier/ heme binding / iron ion binding / monooxygenase/ oxygen binding (TAIR:AT4G37370.1); Has 23736 Blast hits to 23615 proteins in 1268 species: Archae - 32; Bacteria - 2353; Metazoa - 10314; Fungi - 4434; Plants - 5673; Viruses - 3; Other Eukaryotes - 927 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process oxidation-reduction process molecular function electron carrier activity heme binding iron ion binding oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
Pathway	Reactome REACT_13433
Sequence	AT4G37310.1 | Genomic | mRNA | CDS | Protein
Microarray
Sampling	Buchanan-Wollaston V, Page T, Harrison E, Breeze E, Lim PO, Nam HG, Lin JF, Wu SH, Swidzinski J, Ishizaki K, Leaver CJ. Comparative transcriptome analysis reveals significant differences in gene expression and signalling pathways between developmental and dark/starvation-induced senescence in Arabidopsis. Plant J. 2005 May;42(4)
Comparation	Legends: Col: wild type, indicates the ratio of expression in senescing leaves/green leaves. NahG, coi1 and ein2: indicates the ratio of expression in senescing leaves of mutant/senescing wild type. D/L: ratio of DARK 5d/control. CD: Cell Death, ratio of starved cell suspension culture/control. Genes showing at least 3 fold (ratio) up regulation during leaf senescence.
Ortholog Group
Ortholog Groups: OG5_134366	Accession Taxon NP_197962 Arabidopsis thaliana NP_568024 ( AT4G37310 ) Arabidopsis thaliana NP_001057429 Oryza sativa Japonica Group NP_001057903 Oryza sativa Japonica Group NP_001057905 Oryza sativa Japonica Group NP_001057907 Oryza sativa Japonica Group NP_001057909 Oryza sativa Japonica Group NP_001057912 Oryza sativa Japonica Group e_gw1.334.32.1 Physcomitrella patens subsp. patens 30170.m013942 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24298 3.6E-91 4 513 No hit NA Pfam PF00067 4.7E-92 31 490 IPR001128 Cytochrome P450 SUPERFAMILY SSF48264 6.3E-114 31 500 IPR001128 Cytochrome P450 PRINTS PR00463 9.6E-43 60 79 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 9.6E-43 180 198 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 9.6E-43 294 311 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 8.6E-10 305 322 IPR001128 Cytochrome P450 PRINTS PR00463 9.6E-43 314 340 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 9.6E-43 360 378 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 8.6E-10 361 372 IPR001128 Cytochrome P450 PRINTS PR00463 9.6E-43 401 425 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00463 9.6E-43 436 446 IPR002401 Cytochrome P450, E-class, group I PRINTS PR00385 8.6E-10 437 446 IPR001128 Cytochrome P450 ProSitePatterns PS00086 NA 439 448 IPR017972 Cytochrome P450, conserved site PRINTS PR00463 9.6E-43 446 469 IPR002401 Cytochrome P450, E-class, group I