Basic information
Locus name	AT2G22240
Alias	ATIPS2/MIPS2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Lipid/Carbohydrate metabolism
Effect for Senescence	Unclear
Gene Description	Myo-inositol-1-phosphate synthase isoform 2.
Evidence	Molecular evidence: SSH and Northern [Ref 1]
References	1: Gepstein S, Sabehi G, Carp MJ, Hajouj T, Nesher MF, Yariv I, Dor C, Bassani M Large-scale identification of leaf senescence-associated genes. Plant J. 2003 Dec;36(5):629-42
Gene Ontology	biological process inositol biosynthetic process phospholipid biosynthetic process molecular function inositol-3-phosphate synthase activity
Pathway	KEGG map00521 (EC 5.5.1.4) map00562 (EC 5.5.1.4) MetaCyc PWY-4661
Sequence	AT2G22240.1 | Genomic | mRNA | CDS | Protein AT2G22240.2 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT2G22240.1  miRNA: ath-miR854a miRNA: ath-miR854a mfe: -32.3 kcal/mol  p-value: 0.003965  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.1  miRNA: ath-miR854b miRNA: ath-miR854b mfe: -32.3 kcal/mol  p-value: 0.005203  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.1  miRNA: ath-miR854c miRNA: ath-miR854c mfe: -32.3 kcal/mol  p-value: 0.004054  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.1  miRNA: ath-miR854d miRNA: ath-miR854d mfe: -32.3 kcal/mol  p-value: 0.004064  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.1  miRNA: ath-miR854e miRNA: ath-miR854e mfe: -32.3 kcal/mol  p-value: 0.005253  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.2  miRNA: ath-miR854a miRNA: ath-miR854a mfe: -32.3 kcal/mol  p-value: 0.003960  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.2  miRNA: ath-miR854b miRNA: ath-miR854b mfe: -32.3 kcal/mol  p-value: 0.005197  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.2  miRNA: ath-miR854c miRNA: ath-miR854c mfe: -32.3 kcal/mol  p-value: 0.004049  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.2  miRNA: ath-miR854d miRNA: ath-miR854d mfe: -32.3 kcal/mol  p-value: 0.004059  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'  target: AT2G22240.2  miRNA: ath-miR854e miRNA: ath-miR854e mfe: -32.3 kcal/mol  p-value: 0.005247  position:  53  target 5' G    C   C       U      U 3'             UCCU CCU CUCUGUC CUCGUC              AGGA GGA GGGAUAG GAGUAG   miRNA  3' G                         5'
Ortholog Group
Ortholog Groups: OG5_128316	Accession Taxon NP_179812 ( AT2G22240 ) Arabidopsis thaliana NP_195690 Arabidopsis thaliana NP_196579 Arabidopsis thaliana NP_973509 Arabidopsis thaliana CMR036C Cyanidioschyzon merolae strain 10D 188120 Chlamydomonas reinhardtii ACO68911 Micromonas sp. RCC299 NP_001049242 Oryza sativa Japonica Group NP_001064454 Oryza sativa Japonica Group e_gw1.02.00.172.1 Ostreococcus tauri estExt_Genewise1.C_2670003 Physcomitrella patens subsp. patens estExt_Genewise1.C_550135 Physcomitrella patens subsp. patens 28205.m000068 Ricinus communis e_gw1.12.58.1 Thalassiosira pseudonana CCMP1335 XP_002946886 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11510 5.0E-233 1 380 IPR002587 Myo-inositol-1-phosphate synthase Pfam PF07994 2.2E-91 1 364 IPR002587 Myo-inositol-1-phosphate synthase PIRSF PIRSF015578 7.0E-190 1 380 IPR002587 Myo-inositol-1-phosphate synthase SUPERFAMILY SSF51735 4.1E-113 1 178 No hit NA SUPERFAMILY SSF55347 2.6E-41 179 292 No hit NA Pfam PF01658 4.0E-46 180 293 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like SUPERFAMILY SSF51735 4.1E-113 291 380 No hit NA
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787