Basic information
Locus name	AT3G57880
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	C2 domain-containing protein; FUNCTIONS IN: molecular_function unknown; INVOLVED IN: tryptophan biosynthetic process; LOCATED IN: endoplasmic reticulum, cell wall; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: C2 membrane targeting protein (InterPro:IPR018029), C2 calcium/lipid-binding region, CaLB (InterPro:IPR008973), Phosphoribosyltransferase C-terminal, plant (InterPro:IPR013583), C2 calcium-dependent membrane targeting (InterPro:IPR000008); BEST Arabidopsis thaliana protein match is: C2 domain-containing protein (TAIR:AT1G51570.1); Has 4354 Blast hits to 3163 proteins in 190 species: Archae - 0; Bacteria - 0; Metazoa - 2997; Fungi - 169; Plants - 884; Viruses - 0; Other Eukaryotes - 304 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	molecular function protein binding
Sequence	AT3G57880.1 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT3G57880.1  miRNA: ath-miR4239 miRNA: ath-miR4239 mfe: -29.9 kcal/mol  p-value: 0.003838  position: 2105  target 5' U                     G  3'             GGAGUAUGCGGAGA AGCAAA                 CCUCGUACGCUUUU UUGUUU      miRNA  3'                A         5'
Ortholog Group
Ortholog Groups: OG5_127860	Accession Taxon NP_171911 Arabidopsis thaliana NP_173675 Arabidopsis thaliana NP_175568 Arabidopsis thaliana NP_177610 Arabidopsis thaliana NP_187018 Arabidopsis thaliana NP_191347 ( AT3G57880 ) Arabidopsis thaliana NP_191689 Arabidopsis thaliana NP_191979 Arabidopsis thaliana NP_192898 Arabidopsis thaliana NP_193741 Arabidopsis thaliana NP_196801 Arabidopsis thaliana NP_197299 Arabidopsis thaliana NP_199617 Arabidopsis thaliana NP_568175 Arabidopsis thaliana ACO62542 Micromonas sp. RCC299 ACO65677 Micromonas sp. RCC299 NP_001043430 Oryza sativa Japonica Group NP_001047658 Oryza sativa Japonica Group NP_001048508 Oryza sativa Japonica Group NP_001053064 Oryza sativa Japonica Group NP_001054305 Oryza sativa Japonica Group NP_001054362 Oryza sativa Japonica Group NP_001055351 Oryza sativa Japonica Group NP_001055620 Oryza sativa Japonica Group NP_001058075 Oryza sativa Japonica Group NP_001058966 Oryza sativa Japonica Group NP_001059647 Oryza sativa Japonica Group e_gw1.04.00.295.1 Ostreococcus tauri e_gw1.120.6.1 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_3750002 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2800030 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2800035 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_3750012 Physcomitrella patens subsp. patens fgenesh1_pg.scaffold_69000107 Physcomitrella patens subsp. patens 29216.m000250 Ricinus communis 29269.m000239 Ricinus communis 29885.m000137 Ricinus communis 30072.m000934 Ricinus communis 30072.m000980 Ricinus communis 30074.m001411 Ricinus communis 30147.m014074 Ricinus communis 30152.m002410 Ricinus communis 30169.m006392 Ricinus communis 30174.m009007 Ricinus communis 30190.m011202 Ricinus communis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR10024 0.0 25 772 No hit NA SMART SM00239 9.2E-18 40 136 IPR000008 C2 calcium-dependent membrane targeting SUPERFAMILY SSF49562 3.0E-36 40 177 IPR008973 C2 calcium/lipid-binding domain, CaLB Pfam PF00168 6.2E-20 41 120 IPR000008 C2 calcium-dependent membrane targeting ProSiteProfiles PS50004 15.0 41 121 IPR018029 C2 membrane targeting protein SUPERFAMILY SSF49562 4.7E-33 201 353 IPR008973 C2 calcium/lipid-binding domain, CaLB SMART SM00239 1.0E-12 202 300 IPR000008 C2 calcium-dependent membrane targeting Pfam PF00168 7.3E-15 203 284 IPR000008 C2 calcium-dependent membrane targeting ProSiteProfiles PS50004 13.2 203 285 IPR018029 C2 membrane targeting protein SUPERFAMILY SSF49562 7.7E-28 362 506 IPR008973 C2 calcium/lipid-binding domain, CaLB SMART SM00239 4.0E-12 363 470 IPR000008 C2 calcium-dependent membrane targeting Pfam PF00168 1.9E-14 364 446 IPR000008 C2 calcium-dependent membrane targeting ProSiteProfiles PS50004 9.4 364 455 IPR018029 C2 membrane targeting protein Pfam PF08372 3.4E-82 618 773 IPR013583 Phosphoribosyltransferase C-terminal
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787