Basic information
Locus name	AT4G02570
Alias	ATCUL1
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	ARABIDOPSIS THALIANA CULLIN 1 (ATCUL1); FUNCTIONS IN: protein binding; INVOLVED IN: in 7 processes; LOCATED IN: in 6 components; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Winged helix repressor DNA-binding (InterPro:IPR011991), Cullin homology (InterPro:IPR016158), Cullin, N-terminal region (InterPro:IPR001373), Cullin, conserved site (InterPro:IPR016157), Cullin repeat-like (InterPro:IPR016159); BEST Arabidopsis thaliana protein match is: CUL2 (CULLIN 2); ubiquitin protein ligase binding (TAIR:AT1G02980.1); Has 1654 Blast hits to 1628 proteins in 169 species: Archae - 0; Bacteria - 0; Metazoa - 807; Fungi - 323; Plants - 198; Viruses - 0; Other Eukaryotes - 326 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process ubiquitin-dependent protein catabolic process cellular component cullin-RING ubiquitin ligase complex molecular function ubiquitin protein ligase binding
Pathway
Sequence	AT4G02570.1 | Genomic | mRNA | CDS | Protein AT4G02570.2 | Genomic | mRNA | CDS | Protein AT4G02570.3 | Genomic | mRNA | CDS | Protein AT4G02570.4 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127557	Accession Taxon NP_001031575 Arabidopsis thaliana NP_001031576 ( AT4G02570 ) Arabidopsis thaliana NP_171797 Arabidopsis thaliana NP_175007 Arabidopsis thaliana NP_567243 Arabidopsis thaliana CMT046C Cyanidioschyzon merolae strain 10D 116937 Chlamydomonas reinhardtii ACO62863 Micromonas sp. RCC299 NP_001043048 Oryza sativa Japonica Group NP_001043049 Oryza sativa Japonica Group NP_001054659 Oryza sativa Japonica Group e_gw1.07.00.50.1 Ostreococcus tauri estExt_fgenesh1_pg.C_1440083 Physcomitrella patens subsp. patens estExt_fgenesh1_pm.C_1690020 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1770049 Physcomitrella patens subsp. patens 29726.m004021 Ricinus communis e_gw1.11a.100.1 Thalassiosira pseudonana CCMP1335 estExt_thaps1_ua_kg.C_chr_10086 Thalassiosira pseudonana CCMP1335 XP_002947131 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR11932 0.0 1 738 No hit NA SUPERFAMILY SSF74788 1.6E-107 8 378 IPR016159 Cullin repeat-like-containing domain Pfam PF00888 1.0E-187 21 642 IPR001373 Cullin, N-terminal SUPERFAMILY SSF75632 3.4E-91 382 651 IPR016158 Cullin homology ProSiteProfiles PS50069 50.9 383 613 IPR016158 Cullin homology SMART SM00182 6.1E-84 414 563 IPR016158 Cullin homology SUPERFAMILY SSF46785 4.7E-27 652 738 No hit NA Pfam PF10557 3.8E-28 665 732 IPR019559 Cullin protein, neddylation domain SMART SM00884 2.1E-34 665 732 IPR019559 Cullin protein, neddylation domain ProSitePatterns PS01256 NA 711 738 IPR016157 Cullin, conserved site
Subcellular Localization
Localization 1 Localization nucleus Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization cytosol Evidence SUBAcon Pubmed ID 23180787