Basic information
Locus name	AT4G17170
Alias	RABBL3
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	ARABIDOPSIS RAB GTPASE HOMOLOG B1C (RABB1C); FUNCTIONS IN: GTP binding, GTPase activity; INVOLVED IN: ER to Golgi vesicle-mediated transport, pollen sperm cell differentiation, cell growth; LOCATED IN: plasma membrane, vacuole, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: ATGB2 (GTP-BINDING 2); GTP binding (TAIR:AT4G35860.1); Has 21809 Blast hits to 21762 proteins in 605 species: Archae - 13; Bacteria - 94; Metazoa - 12069; Fungi - 2827; Plants - 1853; Viruses - 19; Other Eukaryotes - 4934 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process small GTPase mediated signal transduction molecular function GTP binding
Pathway	Reactome REACT_11044
Sequence	AT4G17170.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_128031	Accession Taxon NP_193450 ( AT4G17170 ) Arabidopsis thaliana NP_195311 Arabidopsis thaliana CMS346C Cyanidioschyzon merolae strain 10D 148836 Chlamydomonas reinhardtii ACO60748 Micromonas sp. RCC299 NP_001047267 Oryza sativa Japonica Group NP_001053048 Oryza sativa Japonica Group e_gw1.07.00.367.1 Ostreococcus tauri estExt_Genewise1.C_3410059 Physcomitrella patens subsp. patens estExt_Genewise1.C_640127 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1960061 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2150035 Physcomitrella patens subsp. patens 30142.m000636 Ricinus communis gw1.10.194.1 Thalassiosira pseudonana CCMP1335 XP_002954753 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description ProSiteProfiles PS51419 28.5 2 210 No hit NA SUPERFAMILY SSF52540 5.6E-60 2 179 IPR027417 P-loop containing nucleoside triphosphate hydrolase PANTHER PTHR24073 1.1E-141 3 211 No hit NA SMART SM00173 7.3E-38 4 170 IPR020849 Small GTPase superfamily, Ras type PRINTS PR00449 2.3E-42 7 28 IPR001806 Small GTPase superfamily SMART SM00175 4.1E-107 7 170 IPR003579 Small GTPase superfamily, Rab type TIGRFAM TIGR00231 3.5E-33 7 160 IPR005225 Small GTP-binding protein domain Pfam PF00071 4.9E-63 8 168 IPR001806 Small GTPase superfamily SMART SM00174 6.2E-12 9 170 IPR003578 Small GTPase superfamily, Rho type SMART SM00176 7.8E-5 12 211 IPR002041 Ran GTPase PRINTS PR00449 2.3E-42 30 46 IPR001806 Small GTPase superfamily PRINTS PR00449 2.3E-42 48 70 IPR001806 Small GTPase superfamily PRINTS PR00449 2.3E-42 110 123 IPR001806 Small GTPase superfamily PRINTS PR00449 2.3E-42 145 167 IPR001806 Small GTPase superfamily
Subcellular Localization
Localization	endoplasmic reticulum
Evidence	SUBAcon
Pubmed ID	23180787