Basic information
Locus name	AT4G18430
Alias	ATRABA1E
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	Arabidopsis Rab GTPase homolog A1e (AtRABA1e); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab11-related (InterPro:IPR015595); BEST Arabidopsis thaliana protein match is: AtRABA1f (Arabidopsis Rab GTPase homolog A1f); GTP binding (TAIR:AT5G60860.1); Has 22382 Blast hits to 22341 proteins in 612 species: Archae - 21; Bacteria - 99; Metazoa - 12511; Fungi - 2860; Plants - 1871; Viruses - 19; Other Eukaryotes - 5001 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process small GTPase mediated signal transduction molecular function GTP binding
Pathway	Reactome REACT_11044
Sequence	AT4G18430.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126971	Accession Taxon NP_172221 Arabidopsis thaliana NP_172434 Arabidopsis thaliana NP_173136 Arabidopsis thaliana NP_174177 Arabidopsis thaliana NP_180943 Arabidopsis thaliana NP_188124 Arabidopsis thaliana NP_190267 Arabidopsis thaliana NP_193578 ( AT4G18430 ) Arabidopsis thaliana NP_193615 Arabidopsis thaliana NP_199387 Arabidopsis thaliana NP_200723 Arabidopsis thaliana NP_200894 Arabidopsis thaliana CMD062C Cyanidioschyzon merolae strain 10D 195519 Chlamydomonas reinhardtii ACO68773 Micromonas sp. RCC299 NP_001044250 Oryza sativa Japonica Group NP_001044805 Oryza sativa Japonica Group NP_001051744 Oryza sativa Japonica Group NP_001051860 Oryza sativa Japonica Group NP_001054408 Oryza sativa Japonica Group NP_001056048 Oryza sativa Japonica Group NP_001056333 Oryza sativa Japonica Group NP_001057837 Oryza sativa Japonica Group NP_001062887 Oryza sativa Japonica Group estExt_gwp_GeneWisePlus.C_Chr_02.00010460 Ostreococcus tauri estExt_Genewise1.C_2090061 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1570045 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_210151 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_260023 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_840129 Physcomitrella patens subsp. patens 29646.m001115 Ricinus communis 29751.m001858 Ricinus communis 29765.m000724 Ricinus communis 29900.m001554 Ricinus communis 30026.m001462 Ricinus communis 30143.m001211 Ricinus communis 30209.m001527 Ricinus communis estExt_fgenesh1_pg.C_chr_70491 Thalassiosira pseudonana CCMP1335 XP_002950461 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24073 3.0E-123 4 216 No hit NA ProSiteProfiles PS51419 28.3 9 215 No hit NA SUPERFAMILY SSF52540 5.7E-60 9 181 IPR027417 P-loop containing nucleoside triphosphate hydrolase SMART SM00173 1.3E-26 11 177 IPR020849 Small GTPase superfamily, Ras type TIGRFAM TIGR00231 1.8E-40 12 170 IPR005225 Small GTP-binding protein domain PRINTS PR00449 4.9E-42 14 35 IPR001806 Small GTPase superfamily SMART SM00175 7.5E-111 14 177 IPR003579 Small GTPase superfamily, Rab type Pfam PF00071 9.9E-62 15 175 IPR001806 Small GTPase superfamily SMART SM00174 2.0E-12 16 173 IPR003578 Small GTPase superfamily, Rho type SMART SM00176 7.1E-8 19 216 IPR002041 Ran GTPase PRINTS PR00449 4.9E-42 37 53 IPR001806 Small GTPase superfamily PRINTS PR00449 4.9E-42 55 77 IPR001806 Small GTPase superfamily PRINTS PR00449 4.9E-42 117 130 IPR001806 Small GTPase superfamily PRINTS PR00449 4.9E-42 152 174 IPR001806 Small GTPase superfamily
Subcellular Localization
Localization	cytosol
Evidence	SUBAcon
Pubmed ID	23180787