Basic information
Locus name	AT3G42640
Alias	AHA8
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Lipid/Carbohydrate metabolism
Effect for Senescence	unclear
Gene Description	Arabidopsis H(+)-ATPase 8 (AHA8); FUNCTIONS IN: ATPase activity; INVOLVED IN: cation transport, metabolic process, ATP biosynthetic process; LOCATED IN: plasma membrane, membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, P-type, ATPase-associated region (InterPro:IPR008250), ATPase, P-type cation-transporter, N-terminal (InterPro:IPR004014), Haloacid dehalogenase-like hydrolase (InterPro:IPR005834), ATPase, P-type, H+ transporting proton pump (InterPro:IPR000695), ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter (InterPro:IPR001757), ATPase, P-type, plasma-membrane proton-efflux (InterPro:IPR006534), ATPase, P-type phosphorylation site (InterPro:IPR018303); BEST Arabidopsis thaliana protein match is: AHA6 (Arabidopsis H(+)-ATPase 6); ATPase (TAIR:AT2G07560.1); Has 20898 Blast hits to 18521 proteins in 1835 species: Archae - 419; Bacteria - 11597; Metazoa - 3330; Fungi - 1528; Plants - 1082; Viruses - 3; Other Eukaryotes - 2939 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process cation transport cellular component integral to membrane molecular function cation-transporting ATPase activity
Pathway	KEGG map00190 (EC 3.6.3.6)
Sequence	AT3G42640.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127253	Accession Taxon NP_173169 Arabidopsis thaliana NP_178181 Arabidopsis thaliana NP_178762 Arabidopsis thaliana NP_179486 Arabidopsis thaliana NP_180028 Arabidopsis thaliana NP_189850 ( AT3G42640 ) Arabidopsis thaliana NP_190378 Arabidopsis thaliana NP_191592 Arabidopsis thaliana NP_192910 Arabidopsis thaliana NP_194748 Arabidopsis thaliana NP_200545 Arabidopsis thaliana NP_201073 Arabidopsis thaliana CMQ247C Cyanidioschyzon merolae strain 10D 182602 Chlamydomonas reinhardtii 38137 Chlamydomonas reinhardtii 54949 Chlamydomonas reinhardtii ACO63095 Micromonas sp. RCC299 NP_001048395 Oryza sativa Japonica Group NP_001048647 Oryza sativa Japonica Group NP_001049185 Oryza sativa Japonica Group NP_001050947 Oryza sativa Japonica Group NP_001054118 Oryza sativa Japonica Group NP_001055186 Oryza sativa Japonica Group NP_001056980 Oryza sativa Japonica Group NP_001059093 Oryza sativa Japonica Group NP_001061339 Oryza sativa Japonica Group NP_001067382 Oryza sativa Japonica Group gw1.06.00.30.1 Ostreococcus tauri e_gw1.404.27.1 Physcomitrella patens subsp. patens estExt_fgenesh2_pg.C_1370088 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_3210018 Physcomitrella patens subsp. patens 27401.m000290 Ricinus communis 29588.m000874 Ricinus communis 29737.m001242 Ricinus communis 29810.m000144 Ricinus communis 29822.m003460 Ricinus communis 29848.m004445 Ricinus communis 29884.m000180 Ricinus communis 30147.m014059 Ricinus communis 30174.m008765 Ricinus communis 30182.m000136 Ricinus communis fgenesh1_pg.C_chr_7000651 Thalassiosira pseudonana CCMP1335 XP_002947352 Volvox carteri f. nagariensis XP_002951653 Volvox carteri f. nagariensis XP_002951750 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24093 0.0 4 884 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 1.3E-87 15 133 No hit NA SMART SM00831 3.2E-21 16 88 IPR004014 Cation-transporting P-type ATPase, N-terminal Pfam PF00690 1.1E-12 19 82 IPR004014 Cation-transporting P-type ATPase, N-terminal TIGRFAM TIGR01647 0.0 35 807 IPR006534 H+ transporting P-type ATPase, subfamily IIIA Pfam PF00122 6.9E-58 101 322 IPR008250 P-type ATPase, A domain TIGRFAM TIGR01494 9.6E-38 102 350 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81653 6.3E-28 133 230 No hit NA PRINTS PR00119 5.0E-42 180 194 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 1.3E-87 230 324 No hit NA Pfam PF00702 4.4E-22 326 603 IPR023214 HAD-like domain SUPERFAMILY SSF56784 1.7E-37 326 382 IPR023214 HAD-like domain PRINTS PR00119 5.0E-42 330 344 IPR001757 Cation-transporting P-type ATPase ProSitePatterns PS00154 NA 332 338 IPR018303 P-type ATPase, phosphorylation site SUPERFAMILY SSF56784 1.7E-37 419 636 IPR023214 HAD-like domain PRINTS PR00120 4.6E-59 446 464 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 5.0E-42 484 495 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 5.0E-42 506 516 IPR001757 Cation-transporting P-type ATPase PRINTS PR00120 4.6E-59 561 577 IPR001757 Cation-transporting P-type ATPase TIGRFAM TIGR01494 9.4E-29 564 679 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 5.0E-42 589 608 IPR001757 Cation-transporting P-type ATPase PRINTS PR00120 4.6E-59 589 605 IPR001757 Cation-transporting P-type ATPase PRINTS PR00119 5.0E-42 612 624 IPR001757 Cation-transporting P-type ATPase PRINTS PR00120 4.6E-59 620 645 IPR001757 Cation-transporting P-type ATPase SUPERFAMILY SSF81665 1.3E-87 638 847 No hit NA PRINTS PR00120 4.6E-59 761 782 IPR001757 Cation-transporting P-type ATPase Coils Coil NA 899 920 No hit NA
Subcellular Localization
Localization	plasma membrane
Evidence	SUBAcon
Pubmed ID	23180787