Basic information
Locus name	AT4G19640
Alias	ARA7
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Signal transduction
Effect for Senescence	unclear
Gene Description	ARA7; FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579), Rab5-related (InterPro:IPR015599); BEST Arabidopsis thaliana protein match is: RHA1 (RAB HOMOLOG 1); GTP binding (TAIR:AT5G45130.1); Has 21152 Blast hits to 21125 proteins in 588 species: Archae - 19; Bacteria - 100; Metazoa - 11808; Fungi - 2497; Plants - 1845; Viruses - 19; Other Eukaryotes - 4864 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process small GTPase mediated signal transduction molecular function GTP binding
Pathway	Reactome REACT_11044
Sequence	AT4G19640.1 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_126724	Accession Taxon NP_001078287 Arabidopsis thaliana NP_193699 ( AT4G19640 ) Arabidopsis thaliana NP_199326 Arabidopsis thaliana NP_567008 Arabidopsis thaliana 81259 Chlamydomonas reinhardtii ACO62643 Micromonas sp. RCC299 ACO65317 Micromonas sp. RCC299 NP_001048988 Oryza sativa Japonica Group NP_001050846 Oryza sativa Japonica Group NP_001064692 Oryza sativa Japonica Group NP_001067340 Oryza sativa Japonica Group estExt_gwp_GeneWisePlus.C_Chr_08.00010225 Ostreococcus tauri estExt_gwp_gw1.C_1170060 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_2590003 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_380214 Physcomitrella patens subsp. patens fgenesh1_kg.scaffold_543000001 Physcomitrella patens subsp. patens fgenesh2_pg.scaffold_97000056 Physcomitrella patens subsp. patens 29745.m000376 Ricinus communis 29912.m005538 Ricinus communis 30125.m001252 Ricinus communis thaps1_ua_kg.chr_2000205 Thalassiosira pseudonana CCMP1335 XP_002948070 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24073 1.2E-108 6 199 No hit NA ProSiteProfiles PS51419 26.4 6 200 No hit NA SMART SM00173 1.8E-29 8 174 IPR020849 Small GTPase superfamily, Ras type SUPERFAMILY SSF52540 1.0E-55 9 176 IPR027417 P-loop containing nucleoside triphosphate hydrolase PRINTS PR00449 2.4E-37 11 32 IPR001806 Small GTPase superfamily SMART SM00175 9.9E-80 11 174 IPR003579 Small GTPase superfamily, Rab type TIGRFAM TIGR00231 2.0E-28 11 167 IPR005225 Small GTP-binding protein domain Pfam PF00071 2.1E-60 12 171 IPR001806 Small GTPase superfamily SMART SM00174 1.2E-11 13 174 IPR003578 Small GTPase superfamily, Rho type SMART SM00176 1.9E-7 16 193 IPR002041 Ran GTPase PRINTS PR00449 2.4E-37 34 50 IPR001806 Small GTPase superfamily PRINTS PR00449 2.4E-37 52 74 IPR001806 Small GTPase superfamily PRINTS PR00449 2.4E-37 114 127 IPR001806 Small GTPase superfamily PRINTS PR00449 2.4E-37 149 171 IPR001806 Small GTPase superfamily
Subcellular Localization
Localization	endoplasmic reticulum,golgi
Evidence	SUBAcon
Pubmed ID	23180787