Basic information
Locus name	AT3G46060
Alias	ARA3
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Hormone response pathway
Effect for Senescence	unclear
Gene Description	ARA3; FUNCTIONS IN: GTP binding; INVOLVED IN: ethylene mediated signaling pathway; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: Ras-related GTP-binding family protein (TAIR:AT5G59840.1); Has 23629 Blast hits to 23576 proteins in 647 species: Archae - 17; Bacteria - 115; Metazoa - 13122; Fungi - 2888; Plants - 2228; Viruses - 19; Other Eukaryotes - 5240 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process small GTPase mediated signal transduction molecular function GTP binding
Pathway	Reactome REACT_11044
Sequence	AT3G46060.1 | Genomic | mRNA | CDS | Protein AT3G46060.2 | Genomic | mRNA | CDS | Protein AT3G46060.3 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_127321	Accession Taxon NP_001078248 ( AT3G46060 ) Arabidopsis thaliana NP_001078278 Arabidopsis thaliana NP_001118780 Arabidopsis thaliana NP_187601 Arabidopsis thaliana NP_190192 Arabidopsis thaliana NP_190929 Arabidopsis thaliana NP_195972 Arabidopsis thaliana NP_200792 Arabidopsis thaliana NP_850696 Arabidopsis thaliana 195520 Chlamydomonas reinhardtii ACO63409 Micromonas sp. RCC299 NP_001051716 Oryza sativa Japonica Group NP_001055761 Oryza sativa Japonica Group NP_001059259 Oryza sativa Japonica Group e_gw1.05.00.432.1 Ostreococcus tauri estExt_Genewise1.C_2180059 Physcomitrella patens subsp. patens estExt_Genewise1.C_810021 Physcomitrella patens subsp. patens estExt_Genewise1.C_810024 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_1130070 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_880180 Physcomitrella patens subsp. patens 28449.m000019 Ricinus communis 29154.m000216 Ricinus communis e_gw1.3.632.1 Thalassiosira pseudonana CCMP1335 e_gw1.3.633.1 Thalassiosira pseudonana CCMP1335 XP_002955570 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PANTHER PTHR24073 6.4E-165 1 216 No hit NA SMART SM00177 0.0 1 181 IPR024156 Small GTPase superfamily, ARF type ProSiteProfiles PS51419 29.9 11 214 No hit NA SUPERFAMILY SSF52540 1.4E-63 11 190 IPR027417 P-loop containing nucleoside triphosphate hydrolase TIGRFAM TIGR00231 3.2E-31 14 170 IPR005225 Small GTP-binding protein domain PRINTS PR00449 5.0E-46 16 37 IPR001806 Small GTPase superfamily SMART SM00175 2.2E-105 16 180 IPR003579 Small GTPase superfamily, Rab type Pfam PF00071 4.5E-66 17 178 IPR001806 Small GTPase superfamily SMART SM00173 4.7E-35 17 180 IPR020849 Small GTPase superfamily, Ras type SMART SM00174 5.9E-14 18 179 IPR003578 Small GTPase superfamily, Rho type SMART SM00176 3.5E-9 21 213 IPR002041 Ran GTPase PRINTS PR00449 5.0E-46 39 55 IPR001806 Small GTPase superfamily PRINTS PR00449 5.0E-46 57 79 IPR001806 Small GTPase superfamily PRINTS PR00449 5.0E-46 119 132 IPR001806 Small GTPase superfamily PRINTS PR00449 5.0E-46 155 177 IPR001806 Small GTPase superfamily
Subcellular Localization
Localization 1 Localization cytosol Evidence SUBAcon Pubmed ID 23180787
Localization 2 Localization plasma membrane Evidence SUBAcon Pubmed ID 23180787