Basic information
Locus name	AT4G21990
Alias	3-Apr
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others
Effect for Senescence	unclear
Gene Description	APS REDUCTASE 3 (APR3); FUNCTIONS IN: adenylyl-sulfate reductase activity; INVOLVED IN: sulfate assimilation; LOCATED IN: chloroplast; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Rossmann-like alpha/beta/alpha sandwich fold (InterPro:IPR014729), Thioredoxin-independent 5'-adenylylsulphate reductase (InterPro:IPR004508), Thioredoxin fold (InterPro:IPR012335), Phosphoadenosine phosphosulphate reductase (InterPro:IPR002500), Thioredoxin-like (InterPro:IPR017936), Thioredoxin domain (InterPro:IPR013766), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: APR1 (APS REDUCTASE 1); adenylyl-sulfate reductase (TAIR:AT4G04610.1); Has 3878 Blast hits to 3499 proteins in 1032 species: Archae - 84; Bacteria - 1535; Metazoa - 1053; Fungi - 344; Plants - 313; Viruses - 0; Other Eukaryotes - 549 (source: NCBI BLink).
Evidence	Genomic evidence:microarray data [Ref 1]
References	1: Breeze E, Harrison E, McHattie S, Hughes L, Hickman R, Hill C, Kiddle S, Kim YS, Penfold CA, Jenkins D, Zhang C, Morris K, Jenner C, Jackson S, Thomas B, Tabrett A, Legaie R, Moore JD, Wild DL, Ott S, Rand D, Beynon J, Denby K, Mead A, Buchanan-Wollaston High-resolution temporal profiling of transcripts during Arabidopsis leaf senescence reveals a distinct chronology of processes and regulation. Plant Cell 2011 Mar;23(3):873-94
Gene Ontology	biological process metabolic process oxidation-reduction process sulfate reduction molecular function catalytic activity oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
Sequence	AT4G21990.1 | Genomic | mRNA | CDS | Protein AT4G21990.2 | Genomic | mRNA | CDS | Protein
Ortholog Group
Ortholog Groups: OG5_129962	Accession Taxon NP_176409 Arabidopsis thaliana NP_192370 Arabidopsis thaliana NP_193930 ( AT4G21990 ) Arabidopsis thaliana CMT162C Cyanidioschyzon merolae strain 10D 131444 Chlamydomonas reinhardtii ACO67023 Micromonas sp. RCC299 NP_001059750 Oryza sativa Japonica Group 1400010045 Ostreococcus tauri e_gw1.43.3.1 Physcomitrella patens subsp. patens estExt_fgenesh1_kg.C_600002 Physcomitrella patens subsp. patens 29842.m003580 Ricinus communis e_gw1.7.328.1 Thalassiosira pseudonana CCMP1335 estExt_fgenesh1_pg.C_chr_140244 Thalassiosira pseudonana CCMP1335 XP_002947921 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description TIGRFAM TIGR00424 1.9E-181 36 339 IPR004508 Thioredoxin-independent 5'-adenylylsulphate reductase PANTHER PTHR23293 1.8E-23 118 339 No hit NA SUPERFAMILY SSF52402 3.8E-41 120 315 No hit NA Pfam PF01507 2.6E-42 147 327 IPR002500 Phosphoadenosine phosphosulphate reductase
Subcellular Localization
Localization	plastid
Evidence	SUBAcon
Pubmed ID	23180787