Basic information
Locus name	AT4G30210
Alias	ATR2/AR2
Organism	Arabidopsis thaliana
Taxonomic identifier	[NCBI]
Function category	Others:defense
Effect for Senescence	Unclear
Gene Description	Encodes NADPH-cytochrome P450 reductase that catalyzes the first oxidative step of the phenylpropanoid general pathway
Evidence	Molecular evidence: SSH and Northern [Ref 1]
References	1: Gepstein S, Sabehi G, Carp MJ, Hajouj T, Nesher MF, Yariv I, Dor C, Bassani M Large-scale identification of leaf senescence-associated genes. Plant J. 2003 Dec;36(5):629-42
Gene Ontology	biological process oxidation-reduction process molecular function FMN binding NADPH-hemoprotein reductase activity iron ion binding
Sequence	AT4G30210.1 | Genomic | mRNA | CDS | Protein AT4G30210.2 | Genomic | mRNA | CDS | Protein
miRNA Interaction
Details	target: AT4G30210.1  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -29.1 kcal/mol  p-value: 0.001922  position:  570  target 5' C   U            U    G 3'             GGC GAUGAUGAUGAG AUGA              CUG CUACUACUACUU UACU   miRNA  3' A                C      5'  target: AT4G30210.2  miRNA: ath-miR414 miRNA: ath-miR414 mfe: -29.1 kcal/mol  p-value: 0.001919  position:  570  target 5' C   U            U    G 3'             GGC GAUGAUGAUGAG AUGA              CUG CUACUACUACUU UACU   miRNA  3' A                C      5'
Ortholog Group
Ortholog Groups: OG5_127162	Accession Taxon NP_194183 Arabidopsis thaliana NP_194750 Arabidopsis thaliana NP_849472 ( AT4G30210 ) Arabidopsis thaliana CMR440C Cyanidioschyzon merolae strain 10D 116375 Chlamydomonas reinhardtii 188119 Chlamydomonas reinhardtii ACO68950 Micromonas sp. RCC299 NP_001054107 Oryza sativa Japonica Group NP_001061346 Oryza sativa Japonica Group NP_001063914 Oryza sativa Japonica Group e_gw1.01.00.117.1 Ostreococcus tauri e_gw1.260.21.1 Physcomitrella patens subsp. patens e_gw1.34.62.1 Physcomitrella patens subsp. patens estExt_Genewise1.C_1220017 Physcomitrella patens subsp. patens estExt_gwp_gw1.C_5390010 Physcomitrella patens subsp. patens 28402.m000025 Ricinus communis 29908.m006269 Ricinus communis 42772.m000023 Ricinus communis thaps1_ua_kg.chr_20000019 Thalassiosira pseudonana CCMP1335 XP_002946887 Volvox carteri f. nagariensis XP_002953937 Volvox carteri f. nagariensis
Cross Link
Database Entry ID E-value Start End InterPro ID Description PIRSF PIRSF000208 1.4E-185 45 712 IPR023208 NADPH-cytochrome P450 reductase PANTHER PTHR19384 5.6E-268 96 712 No hit NA SUPERFAMILY SSF52218 1.1E-45 102 262 No hit NA ProSiteProfiles PS50902 32.7 105 255 IPR008254 Flavodoxin/nitric oxide synthase PRINTS PR00369 1.5E-22 106 119 IPR001094 Flavodoxin Pfam PF00258 1.4E-35 107 250 IPR008254 Flavodoxin/nitric oxide synthase PRINTS PR00369 1.5E-22 162 173 IPR001094 Flavodoxin PRINTS PR00369 1.5E-22 196 206 IPR001094 Flavodoxin PRINTS PR00369 1.5E-22 220 239 IPR001094 Flavodoxin SUPERFAMILY SSF63380 5.6E-76 302 554 IPR017938 Riboflavin synthase-like beta-barrel Pfam PF00667 4.0E-76 306 529 IPR003097 FAD-binding, type 1 ProSiteProfiles PS51384 14.3 310 557 IPR017927 Ferredoxin reductase-type FAD-binding domain PRINTS PR00371 4.1E-36 346 356 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase PRINTS PR00371 4.1E-36 490 497 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase PRINTS PR00371 4.1E-36 524 533 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase SUPERFAMILY SSF52343 1.3E-48 553 712 No hit NA PRINTS PR00371 4.1E-36 565 584 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase Pfam PF00175 9.9E-19 566 676 IPR001433 Oxidoreductase FAD/NAD(P)-binding PRINTS PR00371 4.1E-36 594 603 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase PRINTS PR00371 4.1E-36 607 618 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase PRINTS PR00371 4.1E-36 638 654 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase PRINTS PR00371 4.1E-36 661 669 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase
Subcellular Localization
Localization 1 Localization ER Evidence Localization with GFP-fusion protein (GFP:cDNA) Pubmed ID 10737809
Localization 2 Localization endoplasmic reticulum Evidence SUBAcon Pubmed ID 23180787